IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques - Test2 - elhamkhani - TriplyDB

IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques

IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques

http://www.wikidata.org/entity/Q24630281

about

Synthetic DNA vaccine strategies against persistent viral infections Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge Interferon induction and function at the mucosal surface.Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions.IFN-λ exerts opposing effects on T cell responses depending on the chronicity of the virus infection.Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction.Type III interferon attenuates a vesicular stomatitis virus-based vaccine vector.Clinical utility of pharmacogenomics in the management of hepatitis C.Dendritic cells in hepatitis C virus infection: key players in the IFNL3-genotype response.Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses.HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo Interferon lambdas: the next cytokine storm Modulation of SIV and HIV DNA vaccine immunity by Fas-FasL signaling HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells.Clinical applications of DNA vaccines: current progress.Cytokines and HCV-related disorders.Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen.Recent advances in the anti-HCV mechanisms of interferon.Gene therapy using plasmid DNA-encoded anti-HER2 antibody for cancers that overexpress HER2.Immunogenicity evaluation of a DNA vaccine expressing the hepatitis C virus non-structural protein 2 gene in C57BL/6 mice Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab.Host genetics in immune-mediated hepatitis C virus clearance.IFN-λs.IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection.Genetics of IL28B and HCV--response to infection and treatment.Polymorphism Near the Interleukin-28B Gene and Anti-Hepatitis C Viral Response.Interferon stimulated genes and innate immune activation following infection with hepatitis B and C viruses.Mgn-3/biobran enhances generation of cytotoxic CD8+ T cells via upregulation of dec-205 expression on dendritic cells.Unique Th1/Th2 phenotypes induced during priming and memory phases by use of interleukin-12 (IL-12) or IL-28B vaccine adjuvants in rhesus macaques.IL28B genetic variation and hepatitis C virus-specific CD4(+) T-cell responses in anti-HCV-positive blood donors.IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes.Regulatory forum opinion piece*: immunotoxicology assessments in nonhuman primates--challenges and opportunities.Interferon Lambda Genetics and Biology in Regulation of Viral Control.Circulating Interferon-λ3, Responsiveness to HBV Vaccination, and HBV/HCV Infections in Haemodialysis Patients.

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P2860

IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques

http://www.wikidata.org/entity/Q24630281

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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IL-28B/IFN-lambda 3 drives gra ...... L killing activity in macaques

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IL-28B/IFN-lambda 3 drives gra ...... L killing activity in macaques

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IL-28B/IFN-lambda 3 drives gra ...... L killing activity in macaques

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IL-28B/IFN-lambda 3 drives gra ...... L killing activity in macaques

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Molecular Therapy

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IL-28B/IFN-lambda 3 drives gra ...... L killing activity in macaques

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Amir S Khan

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David B Weiner

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Devon J Shedlock

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Jian Yan

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Kendra Talbott

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Matthew P Morrow

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Niranjan Y Sardesai

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Panyupa Pankhong

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Roberta Toporovski

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P2860

IL-28, IL-29 and their class II cytokine receptor IL-28R

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity

Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)

The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding

The IFN gamma receptor: a paradigm for cytokine receptor signaling

The receptor of the type I interferon family

Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells

IL-28 and IL-29: newcomers to the interferon family

Antitumor activity of IFN-lambda in murine tumor models

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1714-23

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3492034

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10.1038/MT.2010.118

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9

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20571540

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2956930

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