about
Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesIL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaquesUbiquitination-mediated regulation of interferon responsesInterferon induction by RNA viruses and antagonism by viral pathogensReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingIntermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESYStructural Linkage between Ligand Discrimination and Receptor Activation by Type I InterferonsStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.TYK2 kinase activity is required for functional type I interferon responses in vivoEnhanced production of human influenza virus in PBS-12SF cells with a reduced interferon response.Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneInfluenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosusPathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response.Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.Temporal and spatial resolution of type I and III interferon responses in vivo.Recruitment of histone deacetylase 3 to the interferon-A gene promoters attenuates interferon expressionEnhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosisRole of type I interferon receptor signaling on NK cell development and functionsInterferon-stimulated genes: a complex web of host defenses.Differential activity of type I interferon subtypes for dendritic cell differentiationMutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon betaIFN-ε is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines.Multifaceted activities of type I interferon are revealed by a receptor antagonist.Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptorTyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor.Type I interferon and systemic lupus erythematosus.Total chemical synthesis of human interferon alpha-2b via native chemical ligationEvolutionary genetic dissection of human interferons.Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus InfectionTNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism.Inborn errors of anti-viral interferon immunity in humans.Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced Oncolysis.Siglec-H protects from virus-triggered severe systemic autoimmunity.A Model to Explain How the Bacille Calmette Guérin (BCG) Vaccine Drives Interleukin-12 Production in NeonatesEpstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling propertiesChemical Reaction Network Theory elucidates sources of multistability in interferon signaling.The type I interferons: Basic concepts and clinical relevance in immune-mediated inflammatory diseases.Binding of interferon reduces the force of unfolding for interferon receptor 1.
P2860
Q21131160-034DB6E7-5DD5-46A7-B696-FA8D20C72226Q24630281-E455C770-A44A-43D5-88FD-F49395C1FDC1Q26853323-5732CE50-FBF1-49C7-8275-84101D580C88Q26860007-B4C24752-A9BF-4F77-A615-11A8D8006234Q27310374-C3784725-3B8A-46CE-952E-04EB44854FFFQ27661869-BA5520F8-3480-4D59-A163-AF812C0E655FQ27671836-C6B6BB80-FFD1-405F-A9D7-C5A07CB17F33Q27687338-704C0918-730F-496F-97A4-775772094F97Q28728338-EEC6D2AA-BC21-4B21-8732-A77C93BAEFB0Q30375863-90F05CAA-1BF2-4DB2-976E-8A6B5E89F936Q30597262-5F5FAFDE-7479-4633-A396-5B7AA4C0488BQ33383235-43F39E08-8F43-4F64-9FE7-FEC02902889EQ33804141-B3980ED3-AF9A-4F34-A880-857D1431FD73Q33939691-234F7385-9490-417A-B438-69774AC85149Q33968305-E7C248E5-6909-4A21-98F5-AE9F30FC4137Q34031372-B392C6C3-E417-417A-A380-D6C553259DD5Q34055384-370D6706-3ED6-4CAB-B1CC-D5AC0EAE4724Q34299600-EE351865-EF00-433D-823C-63947C832C0BQ34355672-0C29B2A4-AF5A-421A-ACD7-3070336D69F0Q34380402-9FA211FD-47E0-4B46-BA52-C33BDA86CE98Q34405609-F64B7446-E858-43C8-8E46-1BF53F7D513AQ34615006-9A9959CE-A5A7-4DC4-AE6A-3594C26DB398Q34695472-26FFA463-5E94-4F41-9BFE-3A4114D81855Q34949247-91A5DAB2-6DA0-465F-B5CF-FDC0E46509CBQ35031568-79AC0300-6344-4E8D-9084-1E352E7C8275Q35063016-8C0FA1B3-2615-4F75-8910-F5C423C49B54Q35372365-30621E29-0CD9-42D2-8F58-799BE11E5FBBQ35549980-6EC2F33A-8B05-4FCF-9EE7-A75D1E72F5B2Q35587022-1CE3899F-4B0E-4ADD-957F-ACCB2C835454Q35627683-D5FE21F8-02D2-461B-B7FE-7CDA876E94F8Q35641152-E7A35BB8-3683-4F7E-A348-54A9C3A7871CQ35646047-3E6C7826-1575-4C6D-BFFE-9CD5862FEF69Q35759651-72FAAF22-E51B-42E5-967F-EEEFF0C34E46Q35861186-FE3B9CA3-D2E5-4FB8-9F63-90E4B3191625Q36067728-F13481DD-F6CD-44FF-87A7-A60E4288B57DQ36115881-38995F52-2737-4C92-8B42-BE34940A6087Q36137341-5052F519-6EA6-4AAF-9C0B-F6822701AEF7Q36331912-9DDCA00A-0E36-40E9-85E2-CA5A31153D2DQ36338717-CFA3A5DC-D491-4556-940D-B21325C65F0BQ36344846-9660F88B-A043-482E-8D73-55F45BC3C141
P2860
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The receptor of the type I interferon family
@ast
The receptor of the type I interferon family
@en
The receptor of the type I interferon family
@nl
type
label
The receptor of the type I interferon family
@ast
The receptor of the type I interferon family
@en
The receptor of the type I interferon family
@nl
prefLabel
The receptor of the type I interferon family
@ast
The receptor of the type I interferon family
@en
The receptor of the type I interferon family
@nl
P2093
P3181
P1476
The receptor of the type I interferon family
@en
P2093
P3181
P407
P577
2007-01-01T00:00:00Z