Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein - Test2 - elhamkhani - TriplyDB

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

http://www.wikidata.org/entity/Q24635842

about

SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection New insights into an X-traordinary viral protein SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover Identification and characterization of naturally occurring splice variants of SAMHD1 HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection Mechanism of allosteric activation of SAMHD1 by dGTP Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus The restriction factors of human immunodeficiency virus Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein How SAMHD1 changes our view of viral restriction SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection Guardian of the Human Genome: Host Defense Mechanisms against LINE-1 Retrotransposition Recent Advances in Lentiviral Vaccines for HIV-1 Infection Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?The macrophage: a therapeutic target in HIV-1 infection HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies Evolution of foamy viruses: the most ancient of all retroviruses The role of ubiquitylation in immune defence and pathogen evasion Nonhuman primate models for HIV/AIDS vaccine development Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use A 4-year-old Amish boy with weakness, arthritis, rash, verbal delay, and failure to thrive HIV restriction in quiescent CD4⁺ T cells CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination Host-pathogen interaction in HIV infection The enemy within: endogenous retroelements and autoimmune disease Evolutionary conflicts between viruses and restriction factors shape immunity Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cells Innate immune recognition of HIV-1 Natural SIV hosts: showing AIDS the door Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1 The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells

P2860

Q21089603-3ACF5273-853C-4C2E-B672-6FDABA73A848 Q21131105-9E668F78-EB8D-4A9E-8144-6CCCEB23704A Q21131138-E088BB77-50C1-4BE5-8F93-3DE6B4D7A395 Q21134793-8E8EEC89-C591-4033-B50E-2FCE4A62C265 Q21245040-E2A02B0E-051B-48E7-B919-A76950D14FEC Q24297395-69BEDC4B-AE4F-48D3-BC10-D394D583E64E Q24310328-5CB9F0DA-043E-4BF6-950B-D46EA32C5BE3 Q24336824-52C21237-9454-486B-8A6B-B837A45BE2AF Q24338757-DC226F55-270D-4F66-9DD1-548D5ADD25A8 Q24339547-31EA77F9-A43A-4BD7-99CC-9FE1E6C17C2D Q24498670-99EB75D3-AE0D-4D82-BADF-EBAB49DA5840 Q24605108-385100BE-952B-459B-A52D-34EB32292338 Q24605807-DBBAAC84-31F5-4E6B-AE75-FDF260827811 Q24605899-7838FE1F-A3D7-4594-84F5-42526730BC43 Q24615124-033B5AF9-02CC-4AFD-9052-16BBB46E076A Q24624362-8E38D55A-3B52-4F4F-85FD-6B3E65CD022F Q24634238-A01762A6-6D14-48C5-B2C1-A61630E9628D Q26742086-820460D2-66FC-4C5A-9160-89277C66CE11 Q26742169-E2CF71EB-9993-490B-8543-DEC0ECFA7721 Q26774878-1BA8711A-0C5A-4CE3-BD43-D99F88C7457F Q26785350-CE40A43C-C1EC-4735-9965-F06096A8F320 Q26822422-771CC704-4DDC-4B9B-A296-805BFD5D5919 Q26823236-676A8E53-CE84-487D-8532-451831357AE2 Q26825087-C32F26A3-A444-4EAD-8018-FC8BE06B28D8 Q26852372-DB77D6AA-AFE6-4543-87CB-B30674F55AC1 Q26860775-14E9AE7E-6799-4940-900E-DF0F3EF0D168 Q26861148-F70EEAB8-F085-44C3-B162-CCA8F2C6FCF6 Q26970809-BCF3A121-8D1D-4612-9685-0D0DA24FCBBD Q26995545-637224DA-B2C8-40BC-B469-8F60A220BCB3 Q26995784-CB5C3886-2EDF-4970-8CB8-063CB98D9C3A Q27008186-B761F6CA-172B-4A9E-85AA-06F6D71BC46C Q27009024-A4B2D7EC-E250-46B9-8597-D4EBF9601A6C Q27021785-4CBF1C5E-C25A-4CE4-866E-9D9B8459786A Q27022032-8AAC98F9-C366-4AB6-A115-EBAAC5DF732C Q27022978-1C13D29E-1C58-4A9E-A75E-85154074C611 Q27025598-89C4C8A0-0305-4E86-A9A9-E0E1A3D37E84 Q27026135-DF93E6E6-18E1-444A-B7A6-47295BF848A8 Q27318429-3F336011-481E-49AB-8A67-8386DBEB2DE4 Q27319569-670F4843-69C0-4F1F-A2A6-9672FA2A25F7 Q27319577-1B1609D8-50ED-4B3E-92E2-E78CAC199432

P2860

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

http://www.wikidata.org/entity/Q24635842

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@ast

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@en

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@nl

type

label

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@ast

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@en

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@nl

prefLabel

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@ast

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@en

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@nl

P1433

Q24635842-13519DF6-42B9-4556-8452-037CFA3B76ED

P1476

Q24635842-EE4C78FF-D144-4558-8D29-CB70C7F6E32D

P2093

Q24635842-4449A43C-8151-4156-A10D-E77AAF9AFC24

Q24635842-66EDA4E5-F4C8-44F1-AD70-1620F69B8B22

Q24635842-698DF288-26AB-49BC-BD80-122A928ED356

Q24635842-8B2A118E-5F06-4CC3-9118-0EA3B26DF32D

Q24635842-DCE57B14-DD4E-4C53-ACB2-D226A0857053

Q24635842-DD5F949C-6291-499A-BBB4-643F802BC42E

P2860

Q24635842-0A6A5085-7743-4D67-8207-1368B415ECF8

Q24635842-15558195-D6C4-4F71-8C46-2C740B4D95FC

Q24635842-1933307D-FF91-4786-B53E-283C4C9B6496

Q24635842-220D49A9-E1A7-4869-B2DC-CB54417F2F98

Q24635842-289EEBE3-821C-41EA-93DB-D91445D5A57F

Q24635842-3387A603-C30C-4383-99D8-B445026375C4

Q24635842-3F6DEF87-502A-4CA1-9E2B-F58B745FFFE5

Q24635842-534E05C5-3B71-42E9-8BA7-C832DD043511

Q24635842-6352499E-BBBA-4FB1-BD85-0FF24A79A12C

Q24635842-668A1949-0A21-4E7F-80AE-47E6824A0795

P2888

Q24635842-76872E0D-C9F8-4784-A08E-9F3EBE4E5493

P304

Q24635842-41A840CF-2C7C-4AF5-966B-6F127C391A65

P31

Q24635842-320D0032-999B-4773-9147-D0EF8E8B9E3D

P3181

Q24635842-CCB8655A-66B7-4398-9055-008E0F318A1D

P356

Q24635842-9CF6DFFD-5C20-46E9-AE39-5A739EC9DB76

P407

Q24635842-15DF5AFB-AFA7-4DF3-906A-C254664415B1

P433

Q24635842-0C90E8C1-89AA-4972-8C48-B2A1FD9B3EF3

P478

Q24635842-8941852D-5366-4917-9C74-88DB953D0AE3

P50

Q24635842-231BEC11-F0C9-4E9B-BBAC-B20225FD8503

Q24635842-BB055411-D28D-45FE-822E-734C4FE4563C

Q24635842-EDBD71B6-E73F-4347-B054-1BF36DD71B8D

P577

Q24635842-4CE50005-630D-4554-9EB2-D03FA8ABA64D

P5875

Q24635842-A3957E3E-1D1F-4714-BCD8-241BD66F6148

P6179

Q24635842-13645FE1-4CB9-491F-B5C1-756BD6E57A32

P698

Q24635842-B040B95C-C4AB-4943-A5C9-147457C04A5D

P921

Q24635842-157D770B-5A5A-4733-8103-B780CFCB5F2F

Q24635842-C31810E8-5A9B-4E19-A42E-AA72AA510FA4

P932

Q24635842-2C699B79-6CE8-4BC8-BB3D-9A1CC47CC78F

P3181

P356

P1433

P1476

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

@en

P2093

Caili Hao

http://www.w3.org/2001/XMLSchema#string

Jacek Skowronski

http://www.w3.org/2001/XMLSchema#string

Kasia Hrecka

http://www.w3.org/2001/XMLSchema#string

Magda Gierszewska

http://www.w3.org/2001/XMLSchema#string

Selene K Swanson

http://www.w3.org/2001/XMLSchema#string

Smita Srivastava

http://www.w3.org/2001/XMLSchema#string

P2860

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Trex1 prevents cell-intrinsic initiation of autoimmunity

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

The challenge of viral reservoirs in HIV-1 infection

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

P2888

P304

658-61

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

637050

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NATURE10195

http://www.w3.org/2001/XMLSchema#string

P407

P433

7353

http://www.w3.org/2001/XMLSchema#string

P478

474

http://www.w3.org/2001/XMLSchema#string

P50

Laurence Florens

Michael P. Washburn

Małgorzata Kęsik-Brodacka

P577

2011-06-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51458816

http://www.w3.org/2001/XMLSchema#string

P6179

1037288305

http://www.w3.org/2001/XMLSchema#string

P698

21720370

http://www.w3.org/2001/XMLSchema#string

P921

P932

3179858

http://www.w3.org/2001/XMLSchema#string