Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
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Transmissible Spongiform Encephalopathies Affecting HumansPrion hypothesis: the end of the controversy?The cellular prion protein PrPc is a partner of the Wnt pathway in intestinal epithelial cellsFatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob diseaseStructural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphismA brief history of prionsProfoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases.Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.High-resolution structure of infectious prion protein: the final frontierSingle gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in miceCytosolic PrP can participate in prion-mediated toxicityMouse models for studying the formation and propagation of prions.Strain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171.Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9.De novo prions.Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation.Prions.Review: contribution of transgenic models to understanding human prion disease.Characteristic CSF prion seeding efficiency in humans with prion diseasesTranslation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brainTransgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein.Striatal pathology underlies prion infection-mediated hyperactivity in mice.Requirements for mutant and wild-type prion protein misfolding in vitro.A new mechanism for transmissible prion diseasesInterallelic Transcriptional Enhancement as an in Vivo Measure of Transvection in Drosophila melanogaster.Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein.Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins.Cellular prion protein: from physiology to pathology.Quantifying prion disease penetrance using large population control cohortsPrP(ST), a soluble, protease resistant and truncated PrP form features in the pathogenesis of a genetic prion disease.Pathology of SSLOW, a transmissible and fatal synthetic prion protein disorder, and comparison with naturally occurring classical transmissible spongiform encephalopathies.Ethics in prion disease.Spontaneous generation of infectious prion disease in transgenic mice.Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein.Prion protein misfolding, strains, and neurotoxicity: an update from studies on Mammalian prions.Design and construction of diverse mammalian prion strainsEarly structural features in mammalian prion conformation conversion.Review: membrane-associated misfolded protein propagation in natural transmissible spongiform encephalopathies (TSEs), synthetic prion diseases and Alzheimer's disease.From prion diseases to prion-like propagation mechanisms of neurodegenerative diseases.
P2860
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P2860
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@ast
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@en
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@nl
type
label
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@ast
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@en
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@nl
prefLabel
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@ast
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@en
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@nl
P2093
P2860
P3181
P1433
P1476
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
@en
P2093
Alan Jasanoff
Andrew D Steele
Andrew W Borkowski
Henryk Faas
Nicki Watson
Oliver D King
Walker S Jackson
P2860
P304
P3181
P356
10.1016/J.NEURON.2009.07.026
P407
P577
2009-08-01T00:00:00Z