A general model of prion strains and their pathogenicity
about
Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosisEvidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathyConformational diversity in prion protein variants influences intermolecular beta-sheet formationDarwinian evolution of prions in cell cultureIsolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acidsGenerating a prion with bacterially expressed recombinant prion protein.Cofactor molecules maintain infectious conformation and restrict strain properties in purified prionsSpontaneous generation of prion infectivity in fatal familial insomnia knockin miceA clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New GuineaGenetic susceptibility, evolution and the kuru epidemicPrion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseInsights into Mechanisms of Chronic NeurodegenerationGenetics of Prion Disease in CattlePrion strains and amyloid polymorphism influence phenotypic variationPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersSelf-propagation of pathogenic protein aggregates in neurodegenerative diseasesProgress on low susceptibility mechanisms of transmissible spongiform encephalopathiesTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemYeast prions: structure, biology, and prion-handling systemsAn overview of human prion diseasesThe [RNQ+] prion: a model of both functional and pathological amyloidImplications of prion polymorphismsNeurodegenerative diseases: expanding the prion conceptInsoluble cellular prion protein and its association with prion and Alzheimer diseasesViral quasispecies evolutionTreatment of Prion Disease with Heterologous Prion ProteinsThe strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseThe physical relationship between infectivity and prion protein aggregates is strain-dependentSynthetic prions with novel strain-specified propertiesDe novo generation of infectious prions in vitro produces a new disease phenotypeTransgenic Rabbits Expressing Ovine PrP Are Susceptible to ScrapieIntraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian PrionEvidence that bank vole PrP is a universal acceptor for prionsEx vivo mammalian prions are formed of paired double helical prion protein fibrils.Crystal structure of human prion protein bound to a therapeutic antibodyCrystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion DiseasePrion disease susceptibility is affected by -structure folding propensity and local side-chain interactions in PrPAtomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion DiseaseAtomic structure and hierarchical assembly of a cross- amyloid fibrilAmyloid-associated activity contributes to the severity and toxicity of a prion phenotype
P2860
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P2860
A general model of prion strains and their pathogenicity
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A general model of prion strains and their pathogenicity
@ast
A general model of prion strains and their pathogenicity
@en
A general model of prion strains and their pathogenicity
@nl
type
label
A general model of prion strains and their pathogenicity
@ast
A general model of prion strains and their pathogenicity
@en
A general model of prion strains and their pathogenicity
@nl
prefLabel
A general model of prion strains and their pathogenicity
@ast
A general model of prion strains and their pathogenicity
@en
A general model of prion strains and their pathogenicity
@nl
P2860
P3181
P356
P1433
P1476
A general model of prion strains and their pathogenicity
@en
P2093
Anthony R Clarke
John Collinge
P2860
P3181
P356
10.1126/SCIENCE.1138718
P407
P577
2007-11-09T00:00:00Z