Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest - Test2 - elhamkhani - TriplyDB

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

http://www.wikidata.org/entity/Q24644904

about

Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies Reporter-Expressing, Replicating-Competent Recombinant Arenaviruses Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections Two-photon imaging of microbial immunity in living tissues.Type I interferon suppresses virus-specific B cell responses by modulating CD8(+) T cell differentiation Type I interferon is a therapeutic target for virus-induced lethal vascular damage.New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.Design, synthesis, and biological evaluation of a biyouyanagin compound library Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection Expanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: protein production, antibody production, and in vivo assessment of biological function of genes of interest.Development of live-attenuated arenavirus vaccines based on codon deoptimization RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses.Single nucleoprotein residue modulates arenavirus replication complex formation.Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication.The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity.Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes.D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis Minigenomes, transcription and replication competent virus-like particles and beyond: reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza.A Novel Live Pichinde Virus-Based Vaccine Vector Induces Enhanced Humoral and Cellular Immunity after a Booster Dose.Pathogenesis of Lassa fever virus infection: I. Susceptibility of mice to recombinant Lassa Gp/LCMV chimeric virus.Arenavirus reverse genetics for vaccine development Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.Generation of recombinant arenavirus for vaccine development in FDA-approved Vero cells.pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion.Reverse Genetics Approaches to Control Arenavirus.Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro Current drug discovery strategies against arenavirus infections.Novel drug discovery approaches for treating arenavirus infections.Residues K465 and G467 within the Cytoplasmic Domain of GP2 Play a Critical Role in the Persistence of Lymphocytic Choriomeningitis Virus in Mice.Creation of a recombinant Rift Valley fever virus with a two-segmented genome.Novel strategies for development of hemorrhagic fever arenavirus live-attenuated vaccines.Vaccine platforms to control Lassa fever.

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Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

http://www.wikidata.org/entity/Q24644904

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Generation of recombinant lymp ...... o additional genes of interest

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Generation of recombinant lymp ...... o additional genes of interest

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Generation of recombinant lymp ...... o additional genes of interest

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Generation of recombinant lymp ...... o additional genes of interest

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Proceedings of the National Academy of Sciences of the United States of America

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Generation of recombinant lymp ...... o additional genes of interest

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P2093

Juan C de la Torre

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Lucile Garidou

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Sebastien F Emonet

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P2860

NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs

RNA polymerase I-mediated expression of viral RNA for the rescue of infectious virulent and avirulent Rift Valley fever viruses

Rates of evolutionary change in viruses: patterns and determinants

Arenaviruses: protein structure and function.

Phylogeny of the genus Arenavirus.

Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses.

Transmission of lymphocytic choriomeningitis virus by organ transplantation.

Transcription and RNA replication of tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes

Arenaviruses: genomic RNAs, transcription, and replication.

Fine structure analysis of Pichinde virus nucleocapsids.

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9

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106

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Dorian B McGavern

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23999225

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2651270

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