A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation - Test2 - elhamkhani - TriplyDB

A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation

A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation

http://www.wikidata.org/entity/Q24645087

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ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C Genetic interstitial lung disease Interstitial Lung Disease in Childhood: Clinical and Genetic Aspects Understanding Idiopathic Interstitial Pneumonia: A Gene-Based Review of Stressed Lungs EMT and interstitial lung disease: a mysterious relationship Interstitial lung disease in children Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis Molecular biomarkers in idiopathic pulmonary fibrosis Genetic disorders of surfactant dysfunction The Brichos domain-containing C-terminal part of pro-surfactant protein C binds to an unfolded poly-val transmembrane segment Human surfactant protein A2 gene mutations impair dimmer/trimer assembly leading to deficiency in protein sialylation and secretion C-terminal, endoplasmic reticulum-lumenal domain of prosurfactant protein C - structural features and membrane interactions.Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer.Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis.Gastrokines: stomach-specific proteins with putative homeostatic and tumor suppressor roles.Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis A non-BRICHOS surfactant protein c mutation disrupts epithelial cell function and intercellular signaling Pulmonary alveolar proteinosis in children on La Réunion Island: a new inherited disorder?Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC.Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress.Protein C mutation (A267T) results in ER retention and unfolded protein response activation.Pathogenesis of idiopathic pulmonary fibrosis: review of recent findings.Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia The surfactant protein C mutation A116D alters cellular processing, stress tolerance, surfactant lipid composition, and immune cell activation.Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion.Diseases of pulmonary surfactant homeostasis.Heterozygosity for ABCA3 mutations modifies the severity of lung disease associated with a surfactant protein C gene (SFTPC) mutation.A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy Genetics in pulmonary fibrosis--familial cases provide clues to the pathogenesis of idiopathic pulmonary fibrosis.The three R's of lung health and disease: repair, remodeling, and regeneration.Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.A nonaggregating surfactant protein C mutant is misdirected to early endosomes and disrupts phospholipid recycling.Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.Surfactant dysfunction.Genetic Basis of Children's Interstitial Lung Disease.Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies.

P2860

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P2860

A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation

http://www.wikidata.org/entity/Q24645087

description

2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005年の論文

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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American Journal of Respiratory Cell and Molecular Biology

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A surfactant protein C precurs ...... tion, and caspase 3 activation

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Madesh Muniswamy

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Michael F Beers

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Scott J Russo

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Surafel Mulugeta

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Vu Nguyen

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P2860

A stop-codon mutation in the BRI gene associated with familial British dementia

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

Low molecular weight human pulmonary surfactant protein (SP5): isolation, characterization, and cDNA and amino acid sequences

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

A mutation in the surfactant protein C gene associated with familial interstitial lung disease

Interstitial lung disease in a baby with a de novo mutation in the SFTPC gene

Aggresomes: a cellular response to misfolded proteins

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

Biosynthesis of surfactant protein C (SP-C). Sorting of SP-C proprotein involves homomeric association via a signal anchor domain

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endoplasmic reticulum

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2715321

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