A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype
about
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyLife and death of sensory hair cells expressing constitutively active TRPML3The role of TRPMLs in endolysosomal trafficking and functionPermeation, regulation and control of expression of TRP channels by trace metal ionsA TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their ExpulsionRegulation of lysosomal ion homeostasis by channels and transportersMembrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small moleculesGenetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in miceThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsSmall molecule activators of TRPML3Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.Constitutive activity of the human TRPML2 channel induces cell degenerationAberrant Ca2+ handling in lysosomal storage disordersMucolipins: Intracellular TRPML1-3 channelsProperties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation.TRP channels of intracellular membranesHeteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagyThe calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathwayThe Ca(2+) channel TRPML3 regulates membrane trafficking and autophagyA novel ion channel formed by interaction of TRPML3 with TRPV5.Mucolipin-3 regulates luminal calcium, acidification, and membrane fusion in the endosomal pathway.Constitutive activity of TRP channels methods for measuring the activity and its outcome.Role of TRP channels in the cardiovascular system.Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsTRPML: transporters of metals in lysosomes essential for cell survival?Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.Role of TRP channels in the regulation of the endosomal pathway.The intracellular Ca²⁺ channels of membrane traffic.Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1TRPMLs: in sickness and in health.Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.The role of transient receptor potential cation channels in Ca2+ signalingTRP channels.Calcium signaling in membrane repair.The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1.Opening the TRPML gates.TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice.Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
P2860
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P2860
A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@ast
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@en
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@nl
type
label
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@ast
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@en
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@nl
prefLabel
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@ast
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@en
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@nl
P2093
P2860
P3181
P356
P1433
P1476
A novel mode of TRPML3 regulat ...... the varitint-waddler phenotype
@en
P2093
Abigail A Soyombo
Hyun Jin Kim
Kirill Kiselyov
Sandra Tjon-Kon-Sang
Shmuel Muallem
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.56
P407
P577
2008-04-23T00:00:00Z