Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
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BCOR regulates mesenchymal stem cell function by epigenetic mechanismsProgerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblastsA farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse modelHallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsTherapeutic Targeting of TelomeraseMolecular insights into the premature aging disease progeriaWhen lamins go bad: nuclear structure and diseaseAging and longevity in the simplest animals and the quest for immortalitySpinning the web of cell fate.Cellular and molecular biology of aging endothelial cellsThe hallmarks of agingLaminopathies and the long strange trip from basic cell biology to therapyThe nuclear envelope at a glancePotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesRepression of the Antioxidant NRF2 Pathway in Premature AgingEmbryonic senescence and laminopathies in a progeroid zebrafish modelMolecular image analysis: quantitative description and classification of the nuclear lamina in human mesenchymal stem cellsAgeing-related chromatin defects through loss of the NURD complexA progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization.Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model.Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice.Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.Human adult stem cells as the target cells for the initiation of carcinogenesis and for the generation of "cancer stem cells".Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cellDiseases of the nuclear envelope.Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3Lamin-binding ProteinsMechanisms and consequences of aneuploidy and chromosome instability in the aging brainKinase fusions are frequent in Spitz tumours and spitzoid melanomas.Mechanobiology and the microcirculation: cellular, nuclear and fluid mechanics.Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells.Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation.Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence.Nuclear lamins.Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.Identification of mammalian protein quality control factors by high-throughput cellular imagingProgeroid syndromes: models for stem cell aging?Inner nuclear membrane proteins: impact on human disease.
P2860
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P2860
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@ast
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@en
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@nl
type
label
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@ast
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@en
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@nl
prefLabel
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@ast
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@en
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@nl
P2860
P3181
P356
P1433
P1476
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
@en
P2093
Paola Scaffidi
P2860
P2888
P3181
P356
10.1038/NCB1708
P407
P50
P577
2008-04-01T00:00:00Z
P5875
P6179
1036831025