Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. - Test2 - elhamkhani - TriplyDB

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.

http://www.wikidata.org/entity/Q34137401

about

Molecular insights into the premature aging disease progeria Chromatin states and nuclear organization in development--a view from the nuclear lamina When lamins go bad: nuclear structure and disease Mouse models of laminopathies Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biology Embryonic senescence and laminopathies in a progeroid zebrafish model The defective nuclear lamina in Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient and inhibits nuclear localization of Ubc9.Building risk-on-a-chip models to improve breast cancer risk assessment and prevention.Why AMD is a disease of ageing and not of development: mechanisms and insights.Inner nuclear membrane proteins: impact on human disease.The nuclear envelope environment and its cancer connections.DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.Cellular mechanosensing: getting to the nucleus of it all.Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C Can we safely target the WNT pathway?Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.Understanding the roles of nuclear A- and B-type lamins in brain development.Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid Lamins at a glance.The cellular mastermind(?)-mechanotransduction and the nucleus.Nuclear mechanics in disease Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction.Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation Lamins in development, tissue maintenance and stress.Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase Biological aging alters circadian mechanisms in murine adipose tissue depots Sp1 transcription factor interaction with accumulated prelamin a impairs adipose lineage differentiation in human mesenchymal stem cells: essential role of sp1 in the integrity of lipid vesicles.Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation Muscle development, regeneration and laminopathies: how lamins or lamina-associated proteins can contribute to muscle development, regeneration and disease.Cell Mechanosensitivity is Enabled by the LINC Nuclear Complex.Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors.Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development.Adult Stem Cells and Diseases of Aging.Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo.Lamin A, farnesylation and aging The search for evolutionary developmental origins of aging in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system.Hutchinson-Gilford progeria syndrome through the lens of transcription.

P2860

Q26768972-21D95A9C-23F5-44F3-A22F-999A2E6928F7 Q26798007-EAEB8B3B-B902-4D26-80CB-C67FDC93D6D3 Q26827624-B19D98D1-A553-4680-8596-C70004425EFC Q26829927-AA92F17F-6DF4-4DD3-82E8-A1D62AE2304C Q27687804-01A23B72-4113-4DFA-8330-6B04BC43437A Q28477557-C9D724DE-4686-41DB-BBAC-CB89017CBA02 Q30428604-DEA0CE6F-AE9A-46C8-86C1-24A964F22880 Q30431864-839C21AE-0B29-4284-B243-C84C18655D86 Q33879659-6EF26D6A-454D-488F-A31F-E6DE18EAF948 Q34252203-8305F64E-03A4-4F4D-9764-A1A52F771CD0 Q34254678-65C7D4ED-3E14-4B96-8315-61D6D2F3F93F Q34480944-74BBFEF9-1A1B-4646-BA05-A80FFC20AB7A Q34614178-787B708D-C7FB-4CA3-9BF9-46230CBC8127 Q35052074-10357F2D-3D88-4F19-AF24-A09B50BC5291 Q35591995-D6510B8A-60E4-4DD3-9D3F-BC947B92A7D8 Q35923515-5FEF4BB3-D18C-4F3F-AFFC-2989CF4E6E2E Q35956784-5ABA7ACE-14FC-45D8-B4CA-7697FDF5FC41 Q35991636-802FE0C4-69AF-4A56-B923-814AD1F14512 Q36010368-98194282-8BAF-4AD5-8A64-3A7C4630AE5F Q36113002-8819EABF-1B2B-4CCF-BB68-442F683BCAE5 Q36144958-0D49BB8B-995E-4BFB-AE20-424F535BC270 Q36158116-01F69823-CC0C-4B76-B801-F8B4631BB4A9 Q36288663-304023FC-914C-46CD-BF96-034D17E3778D Q36418867-2C982108-A0D6-4B98-B0E6-21404AE11661 Q36440522-4BE7437D-E2A9-4317-A9D5-FA37ADB221D3 Q36681467-10662533-B385-4EC4-88D9-B3B9B28278DD Q36795172-D5422239-F5E0-4FFF-A434-E1FF7A0437E9 Q36861511-D3D94A23-9323-4E1B-B31F-81629ED44855 Q36979192-041E9568-AFB8-4AD6-86E8-D059A6CF1582 Q37002317-71C7CCE6-F571-4ED3-8CC9-2334D5440794 Q37016154-C1B77C85-1378-43E8-A205-337ADD6F8F66 Q37136532-9656E890-6329-4B63-99BD-E0A10989FBB7 Q37200843-4BAD2A89-76EF-4E0A-98A6-70D404290431 Q37463359-654C5008-3FA5-4E68-97C4-F968C776F321 Q37503436-C641C644-3B8A-4A21-BA10-A206C58A0950 Q37711264-81BA1ED5-19C2-4599-A3BC-31610193FDD8 Q37901523-54805052-CA2A-4ED2-91C0-4E893D45A34A Q37922871-6F9FDD84-6CC3-4458-AC88-9003D81A2A0E Q37935721-FA318084-1A33-4C1A-940C-F07B6B55680B Q38089892-894E9245-D706-4730-B28D-8928581C9909

P2860

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.

http://www.wikidata.org/entity/Q34137401

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

Functional coupling between th ...... by Wnt signaling in progeria.

@ast

Functional coupling between th ...... by Wnt signaling in progeria.

@en

Functional coupling between th ...... by Wnt signaling in progeria.

@nl

type

label

Functional coupling between th ...... by Wnt signaling in progeria.

@ast

Functional coupling between th ...... by Wnt signaling in progeria.

@en

Functional coupling between th ...... by Wnt signaling in progeria.

@nl

prefLabel

Functional coupling between th ...... by Wnt signaling in progeria.

@ast

Functional coupling between th ...... by Wnt signaling in progeria.

@en

Functional coupling between th ...... by Wnt signaling in progeria.

@nl

P1433

Q34137401-15411D30-8BF5-44A2-A882-97E6B71B219D

P1476

Q34137401-A668D50D-78B1-4E00-A973-EF56FBE2F0F3

P2093

Q34137401-00906C1B-244B-4893-9B28-AD43763FCBC8

Q34137401-0E2061CF-F5C5-40F1-BBAB-AC8DC59CBF34

Q34137401-0E95667C-867B-480F-ADCB-4C2ABC999619

Q34137401-4930A470-C0E7-40EF-9FAA-718AA4F47804

Q34137401-4B8B37C3-EC4A-415C-8B12-B4C7D716F024

Q34137401-66DDF1CE-EBF8-4006-8A90-9406C373C2C8

Q34137401-8006EE55-D8BD-4CC9-828F-BCB203B529EB

Q34137401-8B1323C3-584C-4212-B31B-18493CC61C12

Q34137401-8F6E7EC8-DC82-4CA1-80D5-5FD68FD2EDA3

Q34137401-9A1EBAA9-0426-4AFD-8A51-AD7A22D68112

P2860

Q34137401-041FA116-0227-4B80-996C-0FBD86461D9E

Q34137401-07DB92C7-08A5-4A9A-99EA-DEE6E54CDFEE

Q34137401-07FE365C-7724-4DBF-B876-821B94EFDADB

Q34137401-0AEFC3F5-6440-4D13-869D-A2697C5F1FD9

Q34137401-0BB0A6D0-42CD-4539-830A-A0CE5F8B8C2D

Q34137401-0C3825C7-2DFA-465E-A5DF-EAB4FAFB3FE7

Q34137401-0E84EA55-8142-45FA-A964-7470E48C8215

Q34137401-0E90A82E-7BA1-4D2F-883B-F28757AAD86C

Q34137401-0F0B21D9-E944-41EA-9006-8869AAABBA8D

Q34137401-10555859-B962-4FA1-B1DB-70044CA56518

P304

Q34137401-25F84F1D-318F-4FC7-A9E7-A5CBE1BAFE3B

P31

Q34137401-DCA71E49-AAAA-46D1-BD74-795077D8F47A

P356

Q34137401-1811E40A-934A-4E31-949F-C4744CFDA3CE

P407

Q34137401-EE275FBB-15DB-427D-B9CA-5543C77BF756

P433

Q34137401-2862FB65-9DBC-406A-B4F8-F39F13DCE421

P478

Q34137401-7FDD1022-BD23-470A-8714-0A6B6B512600

P577

Q34137401-2DD61035-9E0A-4A60-8E87-33856D4593E0

P5875

Q34137401-FDD01C3A-53F0-4EEB-A873-172E22802DA8

P698

Q34137401-42AC2C46-A7B5-443D-8AF6-2580B5B30F3C

P921

Q34137401-732E9363-12E6-463E-A896-0A940D316DA5

P932

Q34137401-F7157295-63FE-4573-B1B3-94CB5A0D3BDE

P356

J.DEVCEL.2010.08.013

P1433

Developmental Cell

P1476

Functional coupling between th ...... by Wnt signaling in progeria.

@en

P2093

Alan O Perantoni

http://www.w3.org/2001/XMLSchema#string

Bina Rai

http://www.w3.org/2001/XMLSchema#string

Brian Burke

http://www.w3.org/2001/XMLSchema#string

C Michael Jones

http://www.w3.org/2001/XMLSchema#string

Colin L Stewart

http://www.w3.org/2001/XMLSchema#string

Esther Sook Miin Wong

http://www.w3.org/2001/XMLSchema#string

Honghe Wang

http://www.w3.org/2001/XMLSchema#string

Hyun-Shik Lee

http://www.w3.org/2001/XMLSchema#string

Ira O Daar

http://www.w3.org/2001/XMLSchema#string

Jae-Wook Jeong

http://www.w3.org/2001/XMLSchema#string

P2860

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.

Coupling of the nucleus and cytoplasm: role of the LINC complex

Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility.

Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

P304

413-425

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.DEVCEL.2010.08.013

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P577

2010-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

46219861

http://www.w3.org/2001/XMLSchema#string

P698

20833363

http://www.w3.org/2001/XMLSchema#string

P921

extracellular matrix

P932

2953243

http://www.w3.org/2001/XMLSchema#string