The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
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Molecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosisPre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brainConditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration.The pleiotropic roles of sphingolipid signaling in autophagyAutophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stressMulti-system disorders of glycosphingolipid and ganglioside metabolismAltered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brainsAlterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 proteinSystems biology of the autophagy-lysosomal pathway.The many faces of tauOxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in Niemann-Pick type C disease.The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteinsVertical supranuclear gaze palsy in Niemann-Pick type C disease.Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer's disease: Insights into why statins might not provide clinical benefit.Perspective on innovative therapies for globoid cell leukodystrophy.Checkpoints for Preliminary Identification of Small Molecules found Enriched in Autophagosomes and Activated Mast Cell Secretions Analyzed by Comparative UPLC/MSe.Lysosomal compromise and brain dysfunction: examining the role of neuroaxonal dystrophy.Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice.Markedly perturbed hematopoiesis in acid ceramidase deficient mice.Role of LDL cholesterol and endolysosomes in amyloidogenesis and Alzheimer's disease.Tau normal function influences Niemann-Pick type C disease pathogenesis in mice and modulates autophagy in NPC1-deficient cells.Altered Cholesterol Intracellular Trafficking and the Development of Pathological Hallmarks of Sporadic AD.Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann-Pick type C disease pathogenesis.Aberrant activation of Cdc2/cyclin B1 is involved in initiation of cytoskeletal pathology in murine Niemann-Pick disease type C.
P2860
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P2860
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@ast
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@en
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@nl
type
label
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@ast
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@en
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@nl
prefLabel
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@ast
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@en
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@nl
P2860
P1476
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
@en
P2093
Andrew P Lieberman
Chris D Pacheco
P2860
P356
10.1017/S146239940800080X
P407
P577
2008-01-01T00:00:00Z