The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
about
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaThe HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreNF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosisCeramide channels increase the permeability of the mitochondrial outer membrane to small proteinsCeramide forms channels in mitochondrial outer membranes at physiologically relevant concentrationsCaspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosisTwo distinct pathways leading to nuclear apoptosisMitochondrial release of caspase-2 and -9 during the apoptotic processMechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cellsHepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 ActivationMitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosusBortezomib is cytotoxic to the human growth plate and permanently impairs bone growth in young miceCharacterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compoundBax directly induces release of cytochrome c from isolated mitochondriaTwo CD95 (APO-1/Fas) signaling pathwaysProton MRS imaging in pediatric brain tumors.Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes.Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies.Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signalingPersistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus.Excitotoxins in neuronal apoptosis and necrosis.Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity.Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells.Mitochondrial dysfunction induced by nuclear poly(ADP-ribose) polymerase-1: a treatable cause of cell death in stroke.Meningococcal porin PorB prevents cellular apoptosis in a toll-like receptor 2- and NF-kappaB-independent mannerGene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling.Execution of apoptosis: converging or diverging pathways?Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptorsCommitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2 caspase, and cyclin-dependent kinase activities.Comparison of sensitivity of Th1, Th2, and Th17 cells to Fas-mediated apoptosis.Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation.Energy requirement for caspase activation and neuronal cell death.Molecular identification and interaction assay of the gene (OsUbc13) encoding a ubiquitin-conjugating enzyme in rice.The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosisGranzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.The apoptosome: heart and soul of the cell death machine
P2860
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P2860
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The central executioner of apo ...... and ceramide-induced apoptosis
@ast
The central executioner of apo ...... and ceramide-induced apoptosis
@en
The central executioner of apo ...... and ceramide-induced apoptosis
@nl
type
label
The central executioner of apo ...... and ceramide-induced apoptosis
@ast
The central executioner of apo ...... and ceramide-induced apoptosis
@en
The central executioner of apo ...... and ceramide-induced apoptosis
@nl
prefLabel
The central executioner of apo ...... and ceramide-induced apoptosis
@ast
The central executioner of apo ...... and ceramide-induced apoptosis
@en
The central executioner of apo ...... and ceramide-induced apoptosis
@nl
P2093
P2860
P356
P1476
The central executioner of apo ...... and ceramide-induced apoptosis
@en
P2093
P2860
P356
10.1084/JEM.186.1.25
P407
P577
1997-07-07T00:00:00Z