Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
about
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell deathOverexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerPresence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cellsF1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosisTitanium dioxide (TiO2) nanoparticles induce JB6 cell apoptosis through activation of the caspase-8/Bid and mitochondrial pathwaysMolecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteinsCaspase activation is required for terminal erythroid differentiationThe Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosisInvolvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneSecreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosisPositive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1The subunit CSN6 of the COP9 signalosome is cleaved during apoptosisDEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalFas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivoIn vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domainsThe 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosisIdentification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosisICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme BGeneration of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavageCleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme ACaspases: the executioners of apoptosisCaspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosisHsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate bindingInteraction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor familyA conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitorsCleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosisRereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpointp53-dependent ceramide response to genotoxic stressPurification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteinsThe Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosisCleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosisNAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathwaysIdentification of a new form of death-associated protein kinase that promotes cell survivalThe central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosisThe reactive site loop of the serpin SCCA1 is essential for cysteine proteinase inhibition
P2860
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P2860
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@ast
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@en
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@nl
type
label
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@ast
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@en
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@nl
prefLabel
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@ast
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@en
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@nl
P2093
P3181
P1433
P1476
Yama/CPP32 beta, a mammalian h ...... te poly(ADP-ribose) polymerase
@en
P2093
D R Beidler
G G Poirier
G S Salvesen
K O'Rourke
S Desnoyers
P3181
P356
10.1016/0092-8674(95)90541-3
P407
P577
1995-06-02T00:00:00Z