5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
about
Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteinsZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesDDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signalingSF1 and SF2 helicases: family mattersParamyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon inductionFunction and regulation of retinoic acid-inducible gene-ILGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responsesCytosolic Innate Immune Sensing and Signaling upon InfectionRotavirus non-structural proteins: structure and functionRNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune SignalingEbolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppressionStructural basis for dsRNA recognition and interferon antagonism by Ebola VP35Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-IThe Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal DomainCrystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphateCrystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase ActivityStructures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune SuppressionDefining the functional determinants for RNA surveillance by RIG-ICrystal and solution structure of the human RIG-I SF2 domainEmerging Roles of Protein Deamidation in Innate Immune SignalingRIG-I in RNA virus recognitionLGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signalingInfluenza virus activation of the interferon systemInduction of type I interferon by RNA viruses: cellular receptors and their substratesPathogen recognition by the innate immune system5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication.Sequence-non-specific effects of RNA interference triggers and microRNA regulators.Association of RIG-I with innate immunity of ducks to influenzaSmall non-coding RNAs encoded within the herpes simplex virus type 1 latency associated transcript (LAT) cooperate with the retinoic acid inducible gene I (RIG-I) to induce beta-interferon promoter activity and promote cell survival.Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein.Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-IIncoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signalingHuman neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.Influenza A virus-generated small RNAs regulate the switch from transcription to replication.Immunomodulatory effects of dsRNA and its potential as vaccine adjuvant.A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cellsRecognition of virus infection and innate host responses to viral gene therapy vectors.Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing.RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.
P2860
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P2860
5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@ast
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@en
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@nl
type
label
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@ast
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@en
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@nl
prefLabel
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@ast
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@en
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@nl
P2093
P2860
P3181
P356
P1476
5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I
@en
P2093
Andreas Schmidt
Franziska S Hoffmann
Johannes C Hellmuth
Marie-Cecile Michallet
Michael Wenzel
Robert Besch
Simon Rothenfusser
Stefan Endres
Tobias Schwerd
Wolfgang Hamm
P2860
P304
P3181
P356
10.1073/PNAS.0900971106
P407
P577
2009-07-21T00:00:00Z