The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
about
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesNucleic Acid sensors and type I interferon production in systemic lupus erythematosusZ proteins of New World arenaviruses bind RIG-I and interfere with type I interferon inductionAmbivalent role of the innate immune response in rabies virus pathogenesisImmune signaling by RIG-I-like receptorsReconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunityZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesNLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradationDDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signalingSolution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptorsA shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNAStructure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity responseMeasles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon inductionSF1 and SF2 helicases: family mattersRNA helicases at work: binding and rearrangingChikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoffFunction and regulation of retinoic acid-inducible gene-IInnate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNAPathogen recognition and inflammatory signaling in innate immune defensesLGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-IRegulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6Accessory Factors of Cytoplasmic Viral RNA Sensors Required for Antiviral Innate Immune ResponsedsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effectsPrion-like polymerization as a signaling mechanismMDA5 and LGP2: accomplices and antagonists of antiviral signal transductionTLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesSystems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivityNegative regulation of cytoplasmic RNA-mediated antiviral signalingAgonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity ReceptorThe RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA SensorsNucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling ActivitiesAntiviral immunity in drosophilaRNA conformational changes in the life cycles of RNA viruses, viroids, and virus-associated RNAsStructure of the Ebola VP35 interferon inhibitory domainThe regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA
P2860
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P2860
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@ast
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en-gb
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@nl
type
label
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@ast
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en-gb
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@nl
prefLabel
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@ast
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en-gb
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@nl
P2093
P50
P3181
P1433
P1476
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
@en
P2093
Alfred Lammens
Axel Kirchhofer
Katharina Eisenächer
Katja Lammens
Krzysztof Brzózka
Takashi Fujita
P304
P3181
P356
10.1016/J.MOLCEL.2007.10.032
P407
P577
2008-02-01T00:00:00Z