about
Single-gene mutations and healthy ageing in mammalsCellular ageing mechanisms in osteoarthritisNADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivoThe anti-aging and tumor suppressor protein Klotho enhances differentiation of a human oligodendrocytic hybrid cell lineThe Genomic Scrapheap Challenge; Extracting Relevant Data from Unmapped Whole Genome Sequencing Reads, Including Strain Specific Genomic Segments, in Rats.The renin-angiotensin system and aging in the kidneyThe nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging.Infection and smoking are associated with decreased plasma concentration of the anti-aging protein, α-klothoThe neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model.Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegansThe ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging.Aging and bone.Protective effect of klotho protein against cisplatin ototoxicity in an auditory cell line.Tumour-associated osteomalacia and hypoglycaemia in a patient with prostate cancer: is Klotho involved?A decreased level of serum soluble Klotho is an independent biomarker associated with arterial stiffness in patients with chronic kidney diseaseKlotho and the aging processGeneralized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature agingAblation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho miceKlotho and kidney disease.Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats.Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling PathwaysInsulin, IGF-1 and longevitySuppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation.Long-term Fgf23 deficiency does not influence aging, glucose homeostasis, or fat metabolism in mice with a nonfunctioning vitamin D receptor.Klotho gene polymorphisms are related to colorectal cancer susceptibility.Haplodeficiency of Klotho Gene Causes Arterial Stiffening via Upregulation of Scleraxis Expression and Induction of Autophagy.Promoter methylation and age-related downregulation of Klotho in rhesus monkeyKlotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System.Constitutive expression of human telomerase enhances the proliferation potential of human mesenchymal stem cells.Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation.Loss of Klotho contributes to kidney injury by derepression of Wnt/β-catenin signaling.Klotho, FGF21 and FGF23: Novel Pathways to Musculoskeletal Health?Identification of novel small molecules that elevate Klotho expression.Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification.Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy.G-395A polymorphism in the promoter region of the KLOTHO gene associates with reduced cognitive impairment among the oldest old.The age-regulating protein klotho is vital to sustain retinal function.Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Klotho and aging
@ast
Klotho and aging
@en
Klotho and aging
@nl
type
label
Klotho and aging
@ast
Klotho and aging
@en
Klotho and aging
@nl
prefLabel
Klotho and aging
@ast
Klotho and aging
@en
Klotho and aging
@nl
P2860
P3181
P1476
Klotho and aging
@en
P2093
Makoto Kuro-o
P2860
P304
P3181
P356
10.1016/J.BBAGEN.2009.02.005
P407
P577
2009-10-01T00:00:00Z