Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function - Test2 - elhamkhani - TriplyDB

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

http://www.wikidata.org/entity/Q24655432

about

Chaperone-mediated autophagy: molecular mechanisms and physiological relevance Interplay of LRRK2 with chaperone-mediated autophagy Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)Chaperone-mediated autophagy: a unique way to enter the lysosome world Aging as an event of proteostasis collapse mTOR: from growth signal integration to cancer, diabetes and ageing Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy Protein homeostasis and aging: taking care of proteins from the cradle to the grave Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond Redox control of protein degradation You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging Autophagy, nutrition and immunology The role of autophagy in the pathogenesis of diabetic nephropathy Mitochondrial and skeletal muscle health with advancing age Autophagy and aging Autophagy and apoptosis in liver injury New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart Mitophagy: mechanisms, pathophysiological roles, and analysis Mitochondria and the autophagy-inflammation-cell death axis in organismal aging Emerging novel concept of chaperone therapies for protein misfolding diseases Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Targeting autophagy for the treatment of liver diseases Age effect on myocellular remodeling: response to exercise and nutrition in humans An engineering approach to extending lifespan in C. elegans Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx Autophagy and cardiovascular aging: lesson learned from rapamycin.Autophagy regulates sphingolipid levels in the liver The hallmarks of aging Rapalogs and mTOR inhibitors as anti-aging therapeutics Aging and immune function: molecular mechanisms to interventions AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease Long-term IGF-I exposure decreases autophagy and cell viability.Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver Lysosomal degradation of alpha-synuclein in vivo.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.

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P2860

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

http://www.wikidata.org/entity/Q24655432

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Restoration of chaperone-media ...... intenance and hepatic function

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Cong Zhang

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P2860

Protein measurement with the Folin phenol reagent

A receptor for the selective uptake and degradation of proteins by lysosomes

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation

Autophagy fights disease through cellular self-digestion

Zoxazolamine-induced paralysis in two rat substrains: differences in hepatic drug metabolism

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

Age-related decline in chaperone-mediated autophagy.

Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state.

Evidence for selective mitochondrial autophagy and failure in aging.

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molecular chaperones

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