Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells - Test2 - elhamkhani - TriplyDB

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

http://www.wikidata.org/entity/Q24655659

about

The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans miRNAs in human cancer Molecular basis for interaction of let-7 microRNAs with Lin28 Who Watches the Watchmen: Roles of RNA Modifications in the RNA Interference Pathway The insights of Let-7 miRNAs in oncogenesis and stem cell potency Lin28 and let-7 in cell metabolism and cancer The expanding world of small RNAs in plants RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions Surprises in the 3'-end: 'U' can decide too!MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells Poly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAP RNA protein interaction in neurons MicroRNA biogenesis pathways in cancer Regulation of microRNA biogenesis and turnover by animals and their viruses Genetic variants in microRNA genes: impact on microRNA expression, function, and disease Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression lin-28 controls the succession of cell fate choices via two distinct activities Structure of the Mitochondrial Editosome-Like Complex Associated TUTase 1 Reveals Divergent Mechanisms of UTP Selection and Domain Organization Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28 The Lin28 cold-shock domain remodels pre-let-7 microRNA Crystal Structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting Lin28: primal regulator of growth and metabolism in stem cells Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway An RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It Regulates Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway miRspring: a compact standalone research tool for analyzing miRNA-seq data.Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210.Genomic divergence between the migratory and stationary ecotypes of Atlantic cod.Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.Single-molecule pull-down for investigating protein-nucleic acid interactions.Emergence of chemical biology approaches to the RNAi/miRNA pathway.

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P2860

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

http://www.wikidata.org/entity/Q24655659

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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type

label

Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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prefLabel

Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

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Nature Structural & Molecular Biology

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Lin28 recruits the TUTase Zcch ...... in mouse embryonic stem cells

@en

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Elena Piskounova

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Richard I Gregory

http://www.w3.org/2001/XMLSchema#string

P2860

Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

Selective blockade of microRNA processing by Lin28

Genetic variation in LIN28B is associated with the timing of puberty

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

New ways to meet your (3') end oligouridylation as a step on the path to destruction

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1021-1025

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322068

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10.1038/NSMB.1676

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10

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16

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2009-08-27T00:00:00Z

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1042948549

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19713958

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structural biology

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2758923

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