The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation
about
Scaffold proteins: hubs for controlling the flow of cellular informationJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsRole of Protein Phosphorylation in the Regulation of Cell Cycle and DNA-Related Processes in BacteriaHeterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone ResponseOscillatory stress stimulation uncovers an Achilles' heel of the yeast MAPK signaling networkThe Aspergillus nidulans MAPK module AnSte11-Ste50-Ste7-Fus3 controls development and secondary metabolismConformational Control of the Ste5 Scaffold Protein Insulates Against MAP Kinase MisactivationUnveiling the structural basis for translational ambiguity tolerance in a human fungal pathogenScaffold Protein Ahk1, Which Associates with Hkr1, Sho1, Ste11, and Pbs2, Inhibits Cross Talk Signaling from the Hkr1 Osmosensor to the Kss1 Mitogen-Activated Protein KinaseExploitation of latent allostery enables the evolution of new modes of MAP kinase regulationDpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitmentScaffolds are 'active' regulators of signaling modulesScaffold state switching amplifies, accelerates, and insulates protein kinase C signalingProtein-tyrosine phosphorylation interaction network in Bacillus subtilis reveals new substrates, kinase activators and kinase cross-talkPheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.Signalling ballet in space and timeComputational modeling of cellular signaling processes embedded into dynamic spatial contexts.Signal response sensitivity in the yeast mitogen-activated protein kinase cascadeMolecular characterization of a Fus3/Kss1 type MAPK from Puccinia striiformis f. sp. tritici, PsMAPK1.The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activationThe p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.Protein scaffolds can enhance the bistability of multisite phosphorylation systems.Evolutionary reshaping of fungal mating pathway scaffold proteinsCell signaling in space and time: where proteins come together and when they're apart.Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling outputCdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway.Scaffolds: interaction platforms for cellular signalling circuits.Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase.Computational modeling reveals optimal strategy for kinase transport by microtubules to nerve terminalsThe robustness of a signaling complex to domain rearrangements facilitates network evolution.Ser or Leu: structural snapshots of mistranslation in Candida albicans.IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.Stable Pseudohyphal Growth in Budding Yeast Induced by Synergism between Septin Defects and Altered MAP-kinase SignalingCombined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificityEvolutionary analysis of heterochromatin protein compatibility by interspecies complementation in Saccharomyces.Tighter αC-helix-αL16-helix interactions seem to make p38α less prone to activation by autophosphorylation than Hog1.Mate and fuse: how yeast cells do itJNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinasesArrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding.Sequence patches on MAPK surfaces define protein-protein interactions.
P2860
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P2860
The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@ast
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@en
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@nl
type
label
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@ast
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@en
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@nl
altLabel
The Ste5 Scaffold Directs Mati ...... Fus3 MAP Kinase for Activation
@en
prefLabel
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@ast
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@en
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@nl
P2093
P2860
P3181
P1433
P1476
The Ste5 scaffold directs mati ...... Fus3 MAP kinase for activation
@en
P2093
Attila Reményi
Grace Tang
Julie Singleton
Matthew Good
Wendell A Lim
P2860
P304
P3181
P356
10.1016/J.CELL.2009.01.049
P407
P577
2009-03-20T00:00:00Z