Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation
about
HAM-5 functions as a MAP kinase scaffold during cell fusion in Neurospora crassaGene regulatory network plasticity predates a switch in function of a conserved transcription regulatorPossible mechanism and clinical potentials of allostery.Biophysics of protein evolution and evolutionary protein biophysicsMechanism of arginine sensing by CASTOR1 upstream of mTORC1The Evolutionary Potential of Phenotypic Mutations.Complex regulation of hydrolytic enzyme genes for cellulosic biomass degradation in filamentous fungi.Simple synthetic protein scaffolds can create adjustable artificial MAPK circuits in yeast and mammalian cells.Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites.Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity.Ssp2 Binding Activates the Smk1 Mitogen-Activated Protein Kinase.Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans.Correlated evolution between CK1δ Protein and the Serine-rich Motif Contributes to Regulating the Mammalian Circadian Clock.Mitogen-activated protein kinases, Fus3 and Kss1, regulate chronological lifespan in yeast.An evolution-based strategy for engineering allosteric regulation.Perturbation of the interaction between Gal4p and Gal80p of the Saccharomyces cerevisiae GAL switch results in altered responses to galactose and glucose.Negative Feedback Phosphorylation of Gγ Subunit Ste18 and the Ste5 Scaffold Synergistically Regulates MAPK Activation in Yeast.Hierarchical Organization Endows the Kinase Domain with Regulatory Plasticity
P2860
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P2860
Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
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2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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name
Exploitation of latent alloste ...... modes of MAP kinase regulation
@ast
Exploitation of latent alloste ...... modes of MAP kinase regulation
@en
Exploitation of latent alloste ...... odes of MAP kinase regulation.
@nl
type
label
Exploitation of latent alloste ...... modes of MAP kinase regulation
@ast
Exploitation of latent alloste ...... modes of MAP kinase regulation
@en
Exploitation of latent alloste ...... odes of MAP kinase regulation.
@nl
prefLabel
Exploitation of latent alloste ...... modes of MAP kinase regulation
@ast
Exploitation of latent alloste ...... modes of MAP kinase regulation
@en
Exploitation of latent alloste ...... odes of MAP kinase regulation.
@nl
P2093
P2860
P3181
P1433
P1476
Exploitation of latent alloste ...... modes of MAP kinase regulation
@en
P2093
Jonathan Flores
Scott M Coyle
Wendell A Lim
P2860
P304
P3181
P356
10.1016/J.CELL.2013.07.019
P407
P577
2013-08-15T00:00:00Z