Crystal structure of human CDK4 in complex with a D-type cyclin
about
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseCyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motilityTargeting CDK6 in cancer: State of the art and new insightsA quantitative model for cyclin-dependent kinase control of the cell cycle: revisitedThe structure of CDK4/cyclin D3 has implications for models of CDK activationStructure of FocB--a member of a family of transcription factors regulating fimbrial adhesin expression in uropathogenic Escherichia coliCrystal Structures of Human CaMKIα Reveal Insights into the Regulation Mechanism of CaMKIFragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 InhibitorsAtomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinaseCyclin D as a therapeutic target in cancerFascaplysin as a specific inhibitor for CDK4: insights from molecular modellingDrug targets for cell cycle dysregulators in leukemogenesis: in silico docking studiesAnalysing the Effect of Mutation on Protein Function and Discovering Potential Inhibitors of CDK4: Molecular Modelling and Dynamics StudiesVirtual screening studies reveal linarin as a potential natural inhibitor targeting CDK4 in retinoblastoma.Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states.Cyclin-dependent kinases7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinase.Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21Alternative protein-protein interfaces are frequent exceptions.Molecular mechanism by which palmitate inhibits PKR autophosphorylation.Transcriptome analysis of androgenic gland for discovery of novel genes from the oriental river prawn, Macrobrachium nipponense, using Illumina Hiseq 2000.Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages.Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein.Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study.Methanol extract of wheatgrass induces G1 cell cycle arrest in a p53-dependent manner and down regulates the expression of cyclin D1 in human laryngeal cancer cells-an in vitro and in silico approachAnti-proliferative effects of qianliening capsules on prostatic hyperplasia in vitro and in vivo.Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes.Cyclin D1 as a therapeutic target of renal cell carcinoma- a combined transcriptomics, tissue microarray and molecular docking study from the Kingdom of Saudi Arabia.Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerizationNovel germline CDK4 mutations in patients with head and neck cancerOrphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKsMultifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor.The CDK Network: Linking Cycles of Cell Division and Gene Expression.A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progressionDifferential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.Targeting cell cycle and hormone receptor pathways in cancer.Cyclin-dependent kinase 4 may be expressed as multiple proteins and have functions that are independent of binding to CCND and RB and occur at the S and G 2/M phases of the cell cycle.Selective inhibition of proteins regulating CDK/cyclin complexes: strategy against cancer--a review.
P2860
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P2860
Crystal structure of human CDK4 in complex with a D-type cyclin
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of human CDK4 in complex with a D-type cyclin
@ast
Crystal structure of human CDK4 in complex with a D-type cyclin
@en
Crystal structure of human CDK4 in complex with a D-type cyclin
@nl
type
label
Crystal structure of human CDK4 in complex with a D-type cyclin
@ast
Crystal structure of human CDK4 in complex with a D-type cyclin
@en
Crystal structure of human CDK4 in complex with a D-type cyclin
@nl
prefLabel
Crystal structure of human CDK4 in complex with a D-type cyclin
@ast
Crystal structure of human CDK4 in complex with a D-type cyclin
@en
Crystal structure of human CDK4 in complex with a D-type cyclin
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of human CDK4 in complex with a D-type cyclin
@en
P2093
Anne Cleasby
Finn P Holding
Harren Jhoti
Ian J Tickle
Joe E Coyle
Marc O'Reilly
Philip J Day
Rachel L McMenamin
Rajiv Chopra
P2860
P304
P3181
P356
10.1073/PNAS.0809645106
P407
P577
2009-03-17T00:00:00Z