p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms - Test2 - elhamkhani - TriplyDB

p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

http://www.wikidata.org/entity/Q24657888

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Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1 Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer Inflammatory networks during cellular senescence: causes and consequences.Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.The p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.p38γ mitogen-activated protein kinase contributes to oncogenic properties maintenance and resistance to poly (ADP-ribose)-polymerase-1 inhibition in breast cancer p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion Role of p38 mitogen-activated protein kinase in vascular endothelial aging: interaction with Arginase-II and S6K1 signaling pathway Phosphorylation of Tip60 by p38α regulates p53-mediated PUMA induction and apoptosis in response to DNA damage Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence.Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells.Lamin B1 loss is a senescence-associated biomarker.Inhibition of p38 MAPK attenuates ionizing radiation-induced hematopoietic cell senescence and residual bone marrow injury Human regulatory T cells induce T-lymphocyte senescence.p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261 Interleukin-4 induces senescence in human renal carcinoma cell lines through STAT6 and p38 MAPK.Induction of p38δ expression plays an essential role in oncogenic ras-induced senescence Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells.A posttranslational modification cascade involving p38, Tip60, and PRAK mediates oncogene-induced senescence.Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts.IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways.Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.New Insights into the p38γ and p38δ MAPK Pathways.A simple stochastic model for the feedback circuit between p16INK4a and p53 mediated by p38MAPK: implications for senescence and apoptosis.A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts.p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition.Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma.Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer.Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence.Age-dependent regulation of antioxidant genes by p38α MAPK in the liver.

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P2860

p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

http://www.wikidata.org/entity/Q24657888

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

@wuu

name

p38alpha and p38gamma mediate ...... hrough differential mechanisms

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

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type

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

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prefLabel

p38alpha and p38gamma mediate ...... hrough differential mechanisms

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p38alpha and p38gamma mediate ...... hrough differential mechanisms

@en

p38alpha and p38gamma mediate ...... hrough differential mechanisms

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P1433

Journal of Biological Chemistry

P1476

p38alpha and p38gamma mediate ...... hrough differential mechanisms

@en

P2093

Jiahuai Han

http://www.w3.org/2001/XMLSchema#string

Jinny Kwong

http://www.w3.org/2001/XMLSchema#string

Lixin Hong

http://www.w3.org/2001/XMLSchema#string

Peiqing Sun

http://www.w3.org/2001/XMLSchema#string

Qingdong Deng

http://www.w3.org/2001/XMLSchema#string

Rong Liao

http://www.w3.org/2001/XMLSchema#string

P2860

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

PRAK is essential for ras-induced senescence and tumor suppression

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

PRAK, a novel protein kinase regulated by the p38 MAP kinase

p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

Regulation of PRAK subcellular location by p38 MAP kinases

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

A system for stable expression of short interfering RNAs in mammalian cells

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11237-46

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scholarly article

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2012038

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10.1074/JBC.M808327200

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17

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284

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19251701

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P932

2670128

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