A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts
about
Non-coding RNA: what is functional and what is junk?The case for junk DNARrp6: Integrated roles in nuclear RNA metabolism and transcription terminationProcessing of preribosomal RNA in Saccharomyces cerevisiaeDExD/H-box RNA helicases in ribosome biogenesisNuclear noncoding RNA surveillance: is the end in sight?Structure of an Rrp6–RNA exosome complex bound to poly(A) RNAThe nuclear exosome is active and important during budding yeast meiosis.Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae.Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear ExosomeThe essential nucleolar yeast protein Nop8p controls the exosome function during 60S ribosomal subunit maturationThe Sm complex is required for the processing of non-coding RNAs by the exosomeTrifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational statesBayesian Markov Random Field analysis for protein function prediction based on network dataProgenitor function in self-renewing human epidermis is maintained by the exosome.Comparison of the yeast and human nuclear exosome complexes.The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.Immature large ribosomal subunits containing the 7S pre-rRNA can engage in translation in Saccharomyces cerevisiaeLife without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae.The eukaryotic RNA exosomeYeast nuclear RNA processing.RNA degradation in Saccharomyces cerevisaeForm and function of eukaryotic unstable non-coding RNAs.mRNA quality control pathways in Saccharomyces cerevisiae.Exosome substrate targeting: the long and short of it.The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases.Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression.Cotranscriptional recruitment of RNA exosome cofactors Rrp47p and Mpp6p and two distinct Trf-Air-Mtr4 polyadenylation (TRAMP) complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant messenger ribonucleoprotein particlRrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.The RNA exosome affects iron response and sensitivity to oxidative stressMpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 HelicaseA canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome.RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.The RNA exosome and RNA exosome-linked disease.Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.
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P2860
A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts
description
2008 nî lūn-bûn
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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年论文
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name
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@ast
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@en
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@nl
type
label
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@ast
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@en
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@nl
prefLabel
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@ast
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@en
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@nl
P2860
P50
P921
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P1476
A yeast exosome cofactor, Mpp6 ...... n of noncoding RNA transcripts
@en
P2093
Laurence Decourty
P2860
P304
P356
10.1128/MCB.00463-08
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2008-09-01T00:00:00Z