about
Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ringThree novel components of the human exosomeThe mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturationC1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processingNol9 is a novel polynucleotide 5'-kinase involved in ribosomal RNA processingThe small-subunit processome is a ribosome assembly intermediateRoles of the HEAT repeat proteins Utp10 and Utp20 in 40S ribosome maturationThe zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNASki7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeastContribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6p.ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAsThe N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosomeA yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcriptsThe human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma.Rrp6: Integrated roles in nuclear RNA metabolism and transcription terminationProcessing of preribosomal RNA in Saccharomyces cerevisiaeCrystal structure of an RNA helix recognized by a zinc-finger protein: an 18-bp duplex at 1.6 A resolution.Insights into the mechanism of progressive RNA degradation by the archaeal exosomeNop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast.Nop53p is a novel nucleolar 60S ribosomal subunit biogenesis protein.The nuclear exosome is active and important during budding yeast meiosis.Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic proteinBms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast.Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3.Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae.Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomesThe Saccharomyces cerevisiae small GTPase, Gsp1p/Ran, is involved in 3' processing of 7S-to-5.8S rRNA and in degradation of the excised 5'-A0 fragment of 35S pre-rRNA, both of which are carried out by the exosomeSurveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae.Regulation of unsaturated fatty acid biosynthesis in Saccharomyces: the endoplasmic reticulum membrane protein, Mga2p, a transcription activator of the OLE1 gene, regulates the stability of the OLE1 mRNA through exosome-mediated mechanisms.The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2p) is an essential nucleolar protein required for pre-rRNA processing.Yeast polypeptide exit tunnel ribosomal proteins L17, L35 and L37 are necessary to recruit late-assembling factors required for 27SB pre-rRNA processing.Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.A single subunit, Dis3, is essentially responsible for yeast exosome core activity.5-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs.Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae.Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p.Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Degradation of ribosomal RNA precursors by the exosome
@ast
Degradation of ribosomal RNA precursors by the exosome
@en
Degradation of ribosomal RNA precursors by the exosome
@en-gb
Degradation of ribosomal RNA precursors by the exosome
@nl
type
label
Degradation of ribosomal RNA precursors by the exosome
@ast
Degradation of ribosomal RNA precursors by the exosome
@en
Degradation of ribosomal RNA precursors by the exosome
@en-gb
Degradation of ribosomal RNA precursors by the exosome
@nl
prefLabel
Degradation of ribosomal RNA precursors by the exosome
@ast
Degradation of ribosomal RNA precursors by the exosome
@en
Degradation of ribosomal RNA precursors by the exosome
@en-gb
Degradation of ribosomal RNA precursors by the exosome
@nl
P2093
P2860
P3181
P356
P1476
Degradation of ribosomal RNA precursors by the exosome
@en
P2093
D Tollervey
E Petfalski
P Mitchell
P2860
P304
P3181
P356
10.1093/NAR/28.8.1684
P407
P577
2000-04-01T00:00:00Z