Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence
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Alcoholism: A Systems Approach From Molecular Physiology to Addictive BehaviorNeuropharmacology of alcohol addictionNalmefene: a new approach to the treatment of alcohol dependenceChronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapseZyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of actionA role for brain stress systems in addiction.Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on AddictionThe role of biogenic amine signaling in the bed nucleus of the stria terminals in alcohol abuse.Dynorphin--still an extraordinarily potent opioid peptideA differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegansEffect of chronic ethanol on enkephalin in the hypothalamus and extra-hypothalamic areasDon't stress about CRF: assessing the translational failures of CRF1antagonists.Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonistsAffective cue-induced escalation of alcohol self-administration and increased 22-kHz ultrasonic vocalizations during alcohol withdrawal: role of kappa-opioid receptors.Effects of stress on alcohol drinking: a review of animal studies.Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityActivation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.The one-two punch of alcoholism: role of central amygdala dynorphins/kappa-opioid receptorsNalmefene for the treatment of alcohol use disorders: recent data and clinical potential.The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction.Operant alcohol self-administration in dependent rats: focus on the vapor modelHedonic Homeostatic Dysregulation as a Driver of Drug-Seeking BehaviorPotent inhibition of alcohol self-administration in alcohol-preferring rats by a κ-opioid receptor antagonistEffects of the kappa opioid receptor antagonist, nor-binaltorphimine, on ethanol intake: impact of age and sexEthanol consumption: how should we measure it? Achieving consilience between human and animal phenotypesAcamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent ratsThe role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuseSchedule of passive ethanol exposure affects subsequent intragastric ethanol self-infusionNeurobiology of dysregulated motivational systems in drug addiction.Synthesis and pharmacological evaluation of 6-naltrexamine analogs for alcohol cessation.Opioid modulators for alcohol dependence.Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brainsSystemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats.Opioid receptors and the discriminative stimulus effects of ethanol in squirrel monkeys: Mu and delta opioid receptor mechanismsSafety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11C-LY2795050.Neurobiology of addiction: a neurocircuitry analysis.PET imaging reveals sex differences in kappa opioid receptor availability in humans, in vivoThe epigenetic landscape of alcoholism.Plasticity associated with escalated operant ethanol self-administration during acute withdrawal in ethanol-dependent rats requires intact matrix metalloproteinase systems
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P2860
Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Pharmacological evidence for a ...... systems in ethanol dependence
@ast
Pharmacological evidence for a ...... systems in ethanol dependence
@en
Pharmacological evidence for a ...... systems in ethanol dependence
@nl
type
label
Pharmacological evidence for a ...... systems in ethanol dependence
@ast
Pharmacological evidence for a ...... systems in ethanol dependence
@en
Pharmacological evidence for a ...... systems in ethanol dependence
@nl
prefLabel
Pharmacological evidence for a ...... systems in ethanol dependence
@ast
Pharmacological evidence for a ...... systems in ethanol dependence
@en
Pharmacological evidence for a ...... systems in ethanol dependence
@nl
P2860
P921
P3181
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P1476
Pharmacological evidence for a ...... systems in ethanol dependence
@en
P2093
Brendan M Walker
George F Koob
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P2888
P304
P3181
P356
10.1038/SJ.NPP.1301438
P407
P577
2008-02-01T00:00:00Z
P5875
P6179
1042625896