XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells - Test2 - elhamkhani - TriplyDB

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

http://www.wikidata.org/entity/Q24658399

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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma Emerging functions of the unfolded protein response in immunity Molecular programming of B cell memory Xenobiotic perturbation of ER stress and the unfolded protein response Autophagy in plasma cell pathophysiology Factors regulating immunoglobulin production by normal and disease-associated plasma cells Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes The unfolded protein response in immunity and inflammation The unfolded protein response: from stress pathway to homeostatic regulation Regulated increase in folding capacity prevents unfolded protein stress in the ER.Adjuvant-specific regulation of long-term antibody responses by ZBTB20 Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity.XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis.Regulation of basal cellular physiology by the homeostatic unfolded protein response The stress of protein misfolding: from single cells to multicellular organisms The generation of antibody-secreting plasma cells.Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells.The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer The BiP cochaperone ERdj4 is required for B cell development and function.UPR-Mediated Membrane Biogenesis in B Cells Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation.Phospholipids: "greasing the wheels" of humoral immunity Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease.Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation.The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans.Vitamin A and retinoic acid in the regulation of B-cell development and antibody production.Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila.Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes.Emerging roles for XBP1, a sUPeR transcription factor.The unfolded protein response: how protein folding became a restrictive aspect for innate immunity and B lymphocytes.

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P2860

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

http://www.wikidata.org/entity/Q24658399

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@ast

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@en

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@nl

type

label

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@ast

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@en

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@nl

prefLabel

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@ast

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@en

XBP-1 regulates signal transdu ...... marrow colonization in B cells

@nl

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The EMBO Journal

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XBP-1 regulates signal transdu ...... marrow colonization in B cells

@en

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Chih-Chi Andrew Hu

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Hidde L Ploegh

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J Christopher Love

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Stephanie K Dougan

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P2860

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

Plasma cell differentiation requires the transcription factor XBP-1

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

Regulation and functions of Blimp-1 in T and B lymphocytes

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

Regulation of hepatic lipogenesis by the transcription factor XBP1

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

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1624-36

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scholarly article

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3489226

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10.1038/EMBOJ.2009.117

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11

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28

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Annette M McGehee

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2009-06-03T00:00:00Z

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24394707

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19407814

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2684024

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