XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development - Test2 - elhamkhani - TriplyDB

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

http://www.wikidata.org/entity/Q37377432

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The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule Emerging functions of the unfolded protein response in immunity Molecular programming of B cell memory Factors regulating immunoglobulin production by normal and disease-associated plasma cells The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response The unfolded protein response in immunity and inflammation Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity.Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cells ADAM10 regulates transcription factor expression required for plasma cell function The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.The generation of antibody-secreting plasma cells.The transcription factor XBP1 is selectively required for eosinophil differentiation.Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells.Fyn kinase is required for optimal humoral responses.Plasma cells negatively regulate the follicular helper T cell program The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development.The BiP cochaperone ERdj4 is required for B cell development and function.Viruses, autophagy genes, and Crohn's disease.Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production.UPR-Mediated Membrane Biogenesis in B Cells Myeloid-derived suppressor cells in inflammatory bowel disease.Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo IRE1α activation protects mice against acetaminophen-induced hepatotoxicity XBP1S, a BMP2-inducible transcription factor, accelerates endochondral bone growth by activating GEP growth factor.A Network Model to Describe the Terminal Differentiation of B Cells The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.XBP1S associates with RUNX2 and regulates chondrocyte hypertrophy.B Cells, Antibodies, and More.A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.Phospholipids: "greasing the wheels" of humoral immunity Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response Antioxidant treatment regulates the humoral immune response during acute viral infection.Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function Different B cell populations mediate early and late memory during an endogenous immune response

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XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

http://www.wikidata.org/entity/Q37377432

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

XBP1 governs late events in pl ...... ific memory B cell development

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XBP1 governs late events in pl ...... fic memory B cell development.

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type

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XBP1 governs late events in pl ...... ific memory B cell development

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XBP1 governs late events in pl ...... fic memory B cell development.

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prefLabel

XBP1 governs late events in pl ...... ific memory B cell development

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XBP1 governs late events in pl ...... fic memory B cell development.

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Journal of Experimental Medicine

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XBP1 governs late events in pl ...... ific memory B cell development

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Ann-Hwee Lee

http://www.w3.org/2001/XMLSchema#string

Betty Diamond

http://www.w3.org/2001/XMLSchema#string

Czeslawa Kowal

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Derrick J Todd

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Laurie H Glimcher

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Louise J McHeyzer-Williams

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Michael G McHeyzer-Williams

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P2860

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

Plasma cell differentiation requires the transcription factor XBP-1

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain

B lymphocytes express and lose syndecan at specific stages of differentiation

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

PERK mediates cell-cycle exit during the mammalian unfolded protein response

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

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2151-2159

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scholarly article

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10.1084/JEM.20090738

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10

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206

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2009-09-14T00:00:00Z

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26810184

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19752183

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2757870

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