Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms
about
Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factorA novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/DN-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cellsInhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5.Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein exportThe Ran Pathway in Drosophila melanogaster MitosisChromatin binding of RCC1 during mitosis is important for its nuclear localization in interphaseAccelerating the rate of disassembly of karyopherin.cargo complexes.The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear importMinihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3Anchoring RCC1 by the tailTransport into and out of the nucleus.Identification of a conserved loop in Mog1 that releases GTP from Ran.Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells.The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells.A systems analysis of importin-{alpha}-{beta} mediated nuclear protein importRegulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1.Nup98 is a mobile nucleoporin with transcription-dependent dynamics.Nuclear import of the U1A splicesome protein is mediated by importin alpha /beta and Ran in living mammalian cells.Efficiency, selectivity, and robustness of nucleocytoplasmic transport.Mechanisms and signals for the nuclear import of proteinsKinetic analysis of translocation through nuclear pore complexesSpatial cycles in G-protein crowd controlSolution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPaseThe Drosophila melanogaster importin alpha3 locus encodes an essential gene required for the development of both larval and adult tissues.A streamlined process to phenotypically profile heterologous cDNAs in parallel using yeast cell-based assaysThe nuclear pore complex: nucleocytoplasmic transport and beyond.Nuclear translocation as a novel target for anti-HIV drugs.Functional analysis of key nuclear trafficking components reveals an atypical Ran network required for parasite pathogenesis.Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates.Importin alpha can migrate into the nucleus in an importin beta- and Ran-independent manner.Avian reovirus sigmaA localizes to the nucleolus and enters the nucleus by a nonclassical energy- and carrier-independent pathwayCell cycle-dependent binding modes of the ran exchange factor RCC1 to chromatin.Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62.In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificityAMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.
P2860
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P2860
Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Nuclear import of the ran exch ...... least two distinct mechanisms
@ast
Nuclear import of the ran exch ...... least two distinct mechanisms
@en
Nuclear import of the ran exch ...... least two distinct mechanisms
@nl
type
label
Nuclear import of the ran exch ...... least two distinct mechanisms
@ast
Nuclear import of the ran exch ...... least two distinct mechanisms
@en
Nuclear import of the ran exch ...... least two distinct mechanisms
@nl
prefLabel
Nuclear import of the ran exch ...... least two distinct mechanisms
@ast
Nuclear import of the ran exch ...... least two distinct mechanisms
@en
Nuclear import of the ran exch ...... least two distinct mechanisms
@nl
P2860
P356
P1476
Nuclear import of the ran exch ...... least two distinct mechanisms
@en
P2093
I G Macara
M E Nemergut
P2860
P304
P356
10.1083/JCB.149.4.835
P407
P577
2000-05-01T00:00:00Z