Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells
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N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activitiesThe Nup107-160 nucleoporin complex is required for correct bipolar spindle assemblyThe mechanism of spindle assembly: functions of Ran and its target TPX2HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture."HURP on" we're off to the kinetochore!Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionThe Ran Pathway in Drosophila melanogaster MitosisPhosphorylation by casein kinase 2 regulates Nap1 localization and function.Anchoring RCC1 by the tailRanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubulesDisruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells.Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1.Hyperosmotic stress signaling to the nucleus disrupts the Ran gradient and the production of RanGTPRan is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization.Systematic deletion and mitotic localization of the nuclear pore complex proteins of Aspergillus nidulans.A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytesAnillin-mediated targeting of peanut to pseudocleavage furrows is regulated by the GTPase RanDynamic localisation of Ran GTPase during the cell cycle.TD-60 is required for interphase cell cycle progressionMice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia.Nucleating new branches from oldA membranous spindle matrix orchestrates cell division.Cyclin B-Cdk1 activates its own pump to get into the nucleus.Cell-signalling dynamics in time and space.RanBP1 governs spindle assembly by defining mitotic Ran-GTP production.Determinants of human cyclin B1 association with mitotic chromosomesImportin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner.Phosphorylation of Ran-binding protein-1 by Polo-like kinase-1 is required for interaction with Ran and early mitotic progression.Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear DivisionsA NAD-dependent glutamate dehydrogenase coordinates metabolism with cell division in Caulobacter crescentus.Revisiting chromatin binding of the Arabidopsis UV-B photoreceptor UVR8Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.RanGTP aids anaphase entry through Ubr5-mediated protein turnover.Kinetochore fiber formation in animal somatic cells: dueling mechanisms come to a draw.Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transportNucleosome functions in spindle assembly and nuclear envelope formation.Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin.
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P2860
Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
@wuu
name
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@ast
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en-gb
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@nl
type
label
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@ast
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en-gb
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@nl
prefLabel
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@ast
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en-gb
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@nl
P2860
P921
P3181
P356
P1433
P1476
Phosphorylation of RCC1 in mit ...... le assembly in mammalian cells
@en
P2093
Hoi-Yeung Li
Yixian Zheng
P2860
P304
P3181
P356
10.1101/GAD.1177304
P407
P577
2004-03-01T00:00:00Z