Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes - Test2 - elhamkhani - TriplyDB

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

http://www.wikidata.org/entity/Q24676764

about

A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity.Pouring salt on a wound: Pseudomonas aeruginosa virulence factors alter Na+ and Cl- flux in the lung Protein homeostasis at the plasma membrane ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.Biochemical Basis of the Interaction between Cystic Fibrosis Transmembrane Conductance Regulator and Immunoglobulin-like Repeats of Filamin CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis Airway hydration and COPD The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells Myotonia congenita mutation enhances the degradation of human CLC-1 chloride channels Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect The silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunction LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells.Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions Single-particle tracking of membrane protein diffusion in a potential: simulation, detection, and application to confined diffusion of CFTR Cl- channels.Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging.Early steps in cell infection by parvoviruses: host-specific differences in cell receptor binding but similar endosomal trafficking.The function of the intermediate compartment in pre-Golgi trafficking involves its stable connection with the centrosome Hsp40 chaperones promote degradation of the HERG potassium channel.Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation.Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin Stabilizing rescued surface-localized δf508 CFTR by potentiation of its interaction with Na(+)/H(+) exchanger regulatory factor 1.COMMD1-mediated ubiquitination regulates CFTR trafficking.Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.Applications of proteomic technologies for understanding the premature proteolysis of CFTR.Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells.Quality control for unfolded proteins at the plasma membrane.Functional and trafficking defects in ATP binding cassette A3 mutants associated with respiratory distress syndrome.Beta-2-adrenergic receptor polymorphisms in cystic fibrosis

P2860

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P2860

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

http://www.wikidata.org/entity/Q24676764

description

2004 nî lūn-bûn

@nan

2004 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի մարտին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@ast

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@en

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@nl

type

label

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@ast

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@en

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@nl

prefLabel

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@ast

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@en

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@nl

P1433

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P2860

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P3181

P356

P1433

Journal of Cell Biology

P1476

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

@en

P2093

Blake Papsin

http://www.w3.org/2001/XMLSchema#string

Csilla Nemes

http://www.w3.org/2001/XMLSchema#string

Francesca Pampinella

http://www.w3.org/2001/XMLSchema#string

Jeffrey So

http://www.w3.org/2001/XMLSchema#string

Kai Du

http://www.w3.org/2001/XMLSchema#string

Kristi G Bache

http://www.w3.org/2001/XMLSchema#string

Manu Sharma

http://www.w3.org/2001/XMLSchema#string

Mohamed Benharouga

http://www.w3.org/2001/XMLSchema#string

Noa Zerangue

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

Mechanisms underlying ubiquitination

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.

The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

Receptor downregulation and multivesicular-body sorting

Non-traditional functions of ubiquitin and ubiquitin-binding proteins

Themes and variations on ubiquitylation

Signals for sorting of transmembrane proteins to endosomes and lysosomes

Endocytosis and molecular sorting

P304

923-33

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1721455

http://www.w3.org/2001/XMLSchema#string

P356

10.1083/JCB.200312018

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

164

http://www.w3.org/2001/XMLSchema#string

P50

Harald Stenmark

Gergely L Lukacs

P577

2004-03-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8678020

http://www.w3.org/2001/XMLSchema#string

P698

15007060

http://www.w3.org/2001/XMLSchema#string

P921

quality control

P932

2172283

http://www.w3.org/2001/XMLSchema#string