RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human - Test2 - elhamkhani - TriplyDB

RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human

RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human

http://www.wikidata.org/entity/Q24676838

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TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability The RNA polymerase I transcription machinery RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor Nucleolus: the fascinating nuclear body TIF-IA-dependent regulation of ribosome synthesis in drosophila muscle is required to maintain systemic insulin signaling and larval growth RNA polymerase I-Rrn3 complex at 4.8 Å resolution.Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system.TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3 Ccr4-not regulates RNA polymerase I transcription and couples nutrient signaling to the control of ribosomal RNA biogenesis Evolution of eukaryotic transcription: insights from the genome of Giardia lamblia RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase.In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes.Whole-genome sequencing of a laboratory-evolved yeast strain.Structural mechanism of ATP-independent transcription initiation by RNA polymerase I Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.Wisely chosen paths--regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden.The human genome project: a historical perspective.Conserved regulators of nucleolar size revealed by global phenotypic analyses.UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat.CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction Selective inhibition of rDNA transcription by a small-molecule peptide that targets the interface between RNA polymerase I and Rrn3.RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.Efficient transcription by RNA polymerase I using recombinant core factor.Regulation of ribosomal RNA production by RNA polymerase I: does elongation come first?Active RNA polymerase I of Trypanosoma brucei harbors a novel subunit essential for transcription RNA-polymerase-I-directed rDNA transcription, life and works.The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells.Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway.Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I.Structure of the initiation-competent RNA polymerase I and its implication for transcription.AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply.TIF-IA: An oncogenic target of pre-ribosomal RNA synthesis.New model for the yeast RNA polymerase I transcription cycle.

P2860

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P2860

RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human

http://www.wikidata.org/entity/Q24676838

description

2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2000 թվականի ապրիլին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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RNA polymerase I transcription ...... served between yeast and human

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P1433

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

RNA polymerase I transcription ...... served between yeast and human

@en

P2093

B Moorefield

http://www.w3.org/2001/XMLSchema#string

E A Greene

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R H Reeder

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P2860

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Rapid and efficient site-specific mutagenesis without phenotypic selection

An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae.

The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor.

Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.

RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae.

Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription.

A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae.

RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template.

RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I.

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scholarly article

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10.1073/PNAS.080063997

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9

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97

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12558575

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10758157

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P921

RNA recognition motif domain

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18300

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