Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II
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Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker StudiesSPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63Mutant p53 gain-of-function in cancer.CLIC4 and Schnurri-2: a dynamic duo in TGF-beta signaling with broader implications in cellular homeostasis and disease.Wild-type p53 controls cell motility and invasion by dual regulation of MET expressionMutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).Impaired TGF-β induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.Both ERK/MAPK and TGF-Beta/Smad signaling pathways play a role in the kidney fibrosis of diabetic mice accelerated by blood glucose fluctuation.Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3β.Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer.Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutantRecent advances in p53 research: an interdisciplinary perspective.TP53 drives invasion through expression of its Δ133p53β variant.Differential regulation of the REGγ-proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells.c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expressionp53 and its mutants in tumor cell migration and invasion.Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme.An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression.Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53.The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulationIdentification of GRO1 as a critical determinant for mutant p53 gain of function.Crosstalk between p53 and TGF-β Signalling.The HPV16 E6 oncoprotein and UVB irradiation inhibit the tumor suppressor TGFβ pathway in the epidermis of the K14E6 transgenic mouse.Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene.Role of SMAD proteins in colitis-associated cancer: from known to the unknown.A possible role of vimentin on the cell surface for the activation of latent transforming growth factor-beta.
P2860
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P2860
Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@ast
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@en
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@nl
type
label
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@ast
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@en
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@nl
prefLabel
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@ast
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@en
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@nl
P2093
P2860
P3181
P356
P1476
Mutant p53 attenuates the SMAD ...... n of TGF-beta receptor type II
@en
P2093
Hilla Besserglick
Keren E Shapira
Lilach Weisz
Naomi Goldfinger
Perry Stambolsky
Varda Rotter
Yoav I Henis
Yosef Buganim
P2860
P304
P3181
P356
10.1128/MCB.00374-07
P407
P577
2007-12-01T00:00:00Z