Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant - Test2 - elhamkhani - TriplyDB

Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

http://www.wikidata.org/entity/Q37271710

about

Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2 Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood Activation of the transforming growth factor beta pathway in bacterial otitis media The transcriptome of a complete episode of acute otitis media FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus.Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice Disruption of eyelid and cornea morphogenesis by epithelial β-catenin gain-of-function.Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma Panel 3: Genetics and Precision Medicine of Otitis Media.Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development Unraveling the genetics of otitis media: from mouse to human and back again.Cytokine responses in the common cold and otitis media.What have we learned from murine models of otitis media?The role of vascular endothelial growth factor and vascular stability in diseases of the ear.Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media.A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children.De Novo Variants in the F-Box Protein FBXO11 in 20 Individuals with a Variable Neurodevelopmental Disorder

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Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

http://www.wikidata.org/entity/Q37271710

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 06 July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Regulation of TGF-beta signall ...... Jeff otitis media mouse mutant

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Regulation of TGF-beta signall ...... eff otitis media mouse mutant.

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type

label

Regulation of TGF-beta signall ...... Jeff otitis media mouse mutant

@en

Regulation of TGF-beta signall ...... eff otitis media mouse mutant.

@nl

prefLabel

Regulation of TGF-beta signall ...... Jeff otitis media mouse mutant

@en

Regulation of TGF-beta signall ...... eff otitis media mouse mutant.

@nl

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Regulation of TGF-beta signall ...... Jeff otitis media mouse mutant

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Charlotte Dean

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Helen Hilton

http://www.w3.org/2001/XMLSchema#string

Hilda Tateossian

http://www.w3.org/2001/XMLSchema#string

Maria R Romero

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Rachel E Hardisty-Hughes

http://www.w3.org/2001/XMLSchema#string

Steve Dm Brown

http://www.w3.org/2001/XMLSchema#string

Susan Morse

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The F-box protein family.

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues

FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity

Association of MSX1 and TGFB3 with nonsyndromic clefting in humans

Systematic analysis and nomenclature of mammalian F-box proteins

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II

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scholarly article

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10.1186/1755-8417-2-5

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1

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2009-07-06T00:00:00Z

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26650475

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1006153348

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19580641

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2714483

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