Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon - Test2 - elhamkhani - TriplyDB

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

http://www.wikidata.org/entity/Q24682018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling PTPN14 is required for the density-dependent control of YAP1 Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus Ajuba LIM proteins are negative regulators of the Hippo signaling pathway WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ Molecular mechanism of WW-domain binding protein-2 coactivation function in estrogen receptor signaling β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway PTPN14 interacts with and negatively regulates the oncogenic function of YAP Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways Angiomotin-like proteins associate with and negatively regulate YAP1 Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation TEAD mediates YAP-dependent gene induction and growth control The hippo signaling pathway in development and cancer Structures of YAP protein domains reveal promising targets for development of new cancer drugs α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Structural and functional analysis of the YAP-binding domain of human TEAD2 RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP Expression of Yes-associated protein in common solid tumors Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis Induced Pluripotent Stem Cells: Generation Strategy and Epigenetic Mystery behind Reprogramming YAP-Mediated Mechanotransduction in Skeletal Muscle Emerging role of Hippo pathway in gastric and other gastrointestinal cancers Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Reprogramming cells with synthetic proteins The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Structural insights into the YAP and TEAD complex Structural basis of YAP recognition by TEAD4 in the Hippo pathway Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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P2860

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

http://www.wikidata.org/entity/Q24682018

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2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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type

label

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

@ast

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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prefLabel

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

@ast

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

@en

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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PNAS.0605579103

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Proceedings of the National Academy of Sciences of the United States of America

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

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Beth Muir

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Chu-Xia Deng

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Daniel A Haber

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Dennis C Sgroi

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Gromoslaw A Smolen

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Jianmin Zhang

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Joan S Brugge

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Wenmei Li

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A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

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10.1073/PNAS.0605579103

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103

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Michael Overholtzer

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2006-08-15T00:00:00Z

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