Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate - Test2 - elhamkhani - TriplyDB

Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

http://www.wikidata.org/entity/Q24683820

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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer Centriole assembly and the role of Mps1: defensible or dispensable?FAT10, a ubiquitin-independent signal for proteasomal degradation Glycine-alanine repeats impair proper substrate unfolding by the proteasome The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation Development of a method for screening short-lived proteins using green fluorescent protein Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome: new insights on yeast antizyme.Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome.Targeting proteins for degradation Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase Ubiquitin-independent proteasomal degradation Conformational switching of the 26S proteasome enables substrate degradation Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways The intrinsically disordered N-terminal domain of thymidylate synthase targets the enzyme to the ubiquitin-independent proteasomal degradation pathway Recognition and processing of ubiquitin-protein conjugates by the proteasome Degrons of yeast and mammalian ornithine decarboxylase enzymes make potent combination for regulated targeted protein degradation.Ornithine decarboxylase antizyme finder (OAF): fast and reliable detection of antizymes with frameshifts in mRNAs Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.Epidermal growth factor receptor vIII expression in U87 glioblastoma cells alters their proteasome composition, function, and response to irradiation.Critical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor.Repeat sequence of Epstein-Barr virus-encoded nuclear antigen 1 protein interrupts proteasome substrate processing.Minimal antizyme peptide fully functioning in the binding and inhibition of ornithine decarboxylase and antizyme inhibitor.Functional roles of the dimer-interface residues in human ornithine decarboxylase.Determinants of the differential antizyme-binding affinity of ornithine decarboxylase Paradigms of protein degradation by the proteasome.Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system.Ubiquitin-proteasome pathway and cellular responses to oxidative stress.Antisense-induced ribosomal frameshifting.Timely activation of budding yeast APCCdh1 involves degradation of its inhibitor, Acm1, by an unconventional proteolytic mechanism.Ubiquitin-independent proteasomal degradation during oncogenic viral infections.Cooperation between an intrinsically disordered region and a helical segment is required for ubiquitin-independent degradation by the proteasome Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells.The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease.Structural basis of antizyme-mediated regulation of polyamine homeostasis.Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1.

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P2860

Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

http://www.wikidata.org/entity/Q24683820

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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name

Determinants of proteasome rec ...... biquitin-independent substrate

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Determinants of proteasome rec ...... biquitin-independent substrate

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Determinants of proteasome rec ...... biquitin-independent substrate

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type

label

Determinants of proteasome rec ...... biquitin-independent substrate

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Determinants of proteasome rec ...... biquitin-independent substrate

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Determinants of proteasome rec ...... biquitin-independent substrate

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prefLabel

Determinants of proteasome rec ...... biquitin-independent substrate

@ast

Determinants of proteasome rec ...... biquitin-independent substrate

@en

Determinants of proteasome rec ...... biquitin-independent substrate

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P1433

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P1433

The EMBO Journal

P1476

Determinants of proteasome rec ...... biquitin-independent substrate

@en

P2093

Cecile M Pickart

http://www.w3.org/2001/XMLSchema#string

Mingsheng Zhang

http://www.w3.org/2001/XMLSchema#string

Philip Coffino

http://www.w3.org/2001/XMLSchema#string

P2860

Recognition of the polyubiquitin proteolytic signal

Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases

Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding

The green fluorescent protein

Mechanisms underlying ubiquitination

Multiple associated proteins regulate proteasome structure and function.

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release.

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

The regulatory particle of the Saccharomyces cerevisiae proteasome.

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome.

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1488-96

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10.1093/EMBOJ/CDG158

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7

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22

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2003-04-01T00:00:00Z

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10835824

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12660156

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ubiquitin-proteasome system

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152902

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