Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
about
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathwaysCrif1 is a novel transcriptional coactivator of STAT3STAT1 activation regulates proliferation and differentiation of renal progenitorsInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayGRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interactionSelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cellsgp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathwaysSignal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium.Signaling by STATsJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthmaA Central Role for STAT3 in Gammaherpesvirus-Life Cycle and -DiseasesSkeletal muscle wasting and renewal: a pivotal role of myokine IL-6Mitochondrial Stat3, the Need for Design ThinkingCancer Stem Cell Hierarchy in Glioblastoma MultiformeSignal transducer and activator of transcription 3 regulation by novel binding partnersSTATs: An Old Story, Yet MesmerizingThe Complex Role of STAT3 in Viral InfectionsLIF-STAT signaling and trophoblast biologySTAT3 and the Hyper-IgE syndrome: Clinical presentation, genetic origin, pathogenesis, novel findings and remaining uncertaintiesHyper-IgE syndrome updateSTAT3: A Novel Molecular Mediator of Resistance to ChemoradiotherapyFunctions of the Drosophila JAK-STAT pathway: Lessons from stem cellsAn update on the hyper-IgE syndromesIL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammationThe role of STAT3 in autophagyFER kinase activation of Stat3 is determined by the N-terminal sequenceTip60 is a co-repressor for STAT3Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha componentFunctional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1aSpecific inhibition of Stat3 signal transduction by PIAS3Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancerClinical manifestations, etiology, and pathogenesis of the hyper-IgE syndromesThe LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activitiesA novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocationPhysical and functional interactions between STAT3 and ZIP kinase
P2860
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P2860
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@ast
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@en
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@nl
type
label
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@ast
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@en
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@nl
prefLabel
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@ast
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@en
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@nl
P2093
P2860
P3181
P356
P1476
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
@en
P2093
M Matsumoto
T Kishimoto
P2860
P304
P3181
P356
10.1073/PNAS.94.8.3801
P407
P577
1997-04-15T00:00:00Z