GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction - Test2 - elhamkhani - TriplyDB

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

http://www.wikidata.org/entity/Q24553130

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GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells Crif1 is a novel transcriptional coactivator of STAT3 The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3 ECHS1 interacts with STAT3 and negatively regulates STAT3 signaling Nuclear import of Pin1 is mediated by a novel sequence in the PPIase domain GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I Tyk2 tyrosine kinase expression is required for the maintenance of mitochondrial respiration in primary pro-B lymphocytes Mitochondrial Stat3, the Need for Design Thinking Mitochondrial STAT3 and reactive oxygen species: A fulcrum of adipogenesis?The Hyper-IgE Syndromes: Lessons in Nature, From Bench to Bedside STAT3 as a therapeutic target in head and neck cancer The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation Differentially expressed proteins in malignant and benign adrenocortical tumors Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis.Mitoneet mediates TNFα-induced necroptosis promoted by exposure to fructose and ethanol.GRIM-19 and p16(INK4a) synergistically regulate cell cycle progression and E2F1-responsive gene expression.Transcriptome profiling of estrogen-regulated genes in human primary osteoblasts reveals an osteoblast-specific regulation of the insulin-like growth factor binding protein 4 gene Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth.Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors.GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.Identification of a structural motif in the tumor-suppressive protein GRIM-19 required for its antitumor activity GRIM-19 Expression and Function in Human Gliomas.Cytokine-induced tumor suppressors: a GRIM story Nuclear transcription factors in mammalian mitochondria Down-regulation of GRIM-19 expression is associated with hyperactivation of STAT3-induced gene expression and tumor growth in human cervical cancers.Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.GRIM-19: A Double-edged Sword that Regulates Anti-Tumor and Innate Immune Responses.Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.Suppression of mitochondrial complex I influences cell metastatic properties.Overexpression of GRIM-19, a mitochondrial respiratory chain complex I protein, suppresses hepatocellular carcinoma growth.Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Downregulation of gene expression and activity of GRIM-19 affects mouse oocyte viability, maturation, embryo development and implantation Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma.CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function

P2860

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P2860

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

http://www.wikidata.org/entity/Q24553130

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

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The EMBO Journal

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GRIM-19, a death-regulatory ge ...... ity via functional interaction

@en

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Chengchen Lufei

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Chin Thing Ong

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Guochang Huang

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Jing Ma

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Tong Zhang

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Veronica Novotny-Diermayr

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Xinmin Cao

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P2860

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach

The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6

Endofin, an endosomal FYVE domain protein

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

A family of cytokine-inducible inhibitors of signalling

A new protein containing an SH2 domain that inhibits JAK kinases

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

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1325-35

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scholarly article

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4855317

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10.1093/EMBOJ/CDG135

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6

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22

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2003-03-17T00:00:00Z

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10863202

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12628925

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151078

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