Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes
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PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importPEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteinsPEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders.The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domainPex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.Pex8p, an intraperoxisomal peroxin of Saccharomyces cerevisiae required for protein transport into peroxisomes binds the PTS1 receptor pex5p.Identification of a novel, intraperoxisomal pex14-binding site in pex13: association of pex13 with the docking complex is essential for peroxisomal matrix protein import.Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae.The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae.Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membraneCoa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria.Role of Pex21p for Piggyback Import of Gpd1p and Pnc1p into Peroxisomes of Saccharomyces cerevisiae.Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae.Recognition of peroxisomal targeting signal type 1 by the import receptor Pex5p.Membrane association of the cycling peroxisome import receptor Pex5p.Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteinsThe cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.Ubiquitination of the peroxisomal import receptor Pex5p is required for its recyclingThe peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction.Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites.Peroxisomal membrane proteins insert into the endoplasmic reticulum.Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery.Optimization of specificity in a cellular protein interaction network by negative selection.Potential role for Pex19p in assembly of PTS-receptor docking complexesTrypanosomes contain two highly different isoforms of peroxin PEX13 involved in glycosome biogenesis.Interaction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p.Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down.Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein.Saccharomyces cerevisiae Pex14p contains two independent Pex5p binding sites, which are both essential for PTS1 protein import.A viable Arabidopsis pex13 missense allele confers severe peroxisomal defects and decreases PEX5 association with peroxisomes.The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.How peroxisomes arise.The life cycle of the peroxisome.
P2860
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P2860
Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@ast
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@en
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@nl
type
label
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@ast
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@en
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@nl
prefLabel
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@ast
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@en
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@nl
P2093
P2860
P356
P1476
Involvement of Pex13p in Pex14 ...... rotein import into peroxisomes
@en
P2093
W Girzalsky
P2860
P304
P356
10.1083/JCB.144.6.1151
P407
P577
1999-03-22T00:00:00Z