The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.
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Identification and characterization of the human orthologue of yeast Pex14pPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importAnalysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assayHuman PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctataRhizomelic chondrodysplasia punctata is a peroxisomal protein targeting disease caused by a non-functional PTS2 receptorIdentification of a human PTS1 receptor docking protein directly required for peroxisomal protein importPex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptorPEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteinsPEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.Pex19p, a farnesylated protein essential for peroxisome biogenesis.Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders.A unified nomenclature for peroxisome biogenesis factorsMultiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptorPex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machineryInvolvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomesReevaluation of the role of Pex1 and dynamin-related proteins in peroxisome membrane biogenesisTopography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domainPex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.Pex8p, an intraperoxisomal peroxin of Saccharomyces cerevisiae required for protein transport into peroxisomes binds the PTS1 receptor pex5p.Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membraneIdentification of a novel, intraperoxisomal pex14-binding site in pex13: association of pex13 with the docking complex is essential for peroxisomal matrix protein import.Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import.Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae.Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membraneRecognition of peroxisomal targeting signal type 1 by the import receptor Pex5p.Membrane association of the cycling peroxisome import receptor Pex5p.Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteinsThe peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction.Peroxisomal membrane proteins insert into the endoplasmic reticulum.The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells.Yarrowia lipolytica Pex20p, Saccharomyces cerevisiae Pex18p/Pex21p and mammalian Pex5pL fulfil a common function in the early steps of the peroxisomal PTS2 import pathwayPex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotypeInteraction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p.Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum.Dynamics of gene expression revealed by comparison of serial analysis of gene expression transcript profiles from yeast grown on two different carbon sourcesA hydrogenosome with pyruvate formate-lyase: anaerobic chytrid fungi use an alternative route for pyruvate catabolism.
P2860
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P2860
The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@ast
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@en
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@nl
type
label
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@ast
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@en
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@nl
altLabel
The SH3 domain of the Saccharo ...... mport PTS1-containing proteins
@en
prefLabel
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@ast
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@en
The SH3 domain of the Saccharo ...... port PTS1-containing proteins.
@nl
P2093
P2860
P3181
P356
P1476
The SH3 domain of the Saccharo ...... mport PTS1-containing proteins
@en
P2093
M van den Berg
T Voorn-Brouwer
P2860
P304
P3181
P356
10.1083/JCB.135.1.97
P407
P50
P577
1996-10-01T00:00:00Z