Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region - Test2 - elhamkhani - TriplyDB

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

http://www.wikidata.org/entity/Q24685870

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Regulation of histone deacetylase 4 by binding of 14-3-3 proteins Calreticulin Is a receptor for nuclear export.Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domain MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation Epsin 3 is a novel extracellular matrix-induced transcript specific to wounded epithelia Nucleocytoplasmic shuttling of endocytic proteins MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3 Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2 Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the cytoplasm through nuclear export Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling DcpS scavenger decapping enzyme can modulate pre-mRNA splicing Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions Histone deacetylase 4 possesses intrinsic nuclear import and export signals Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling protein Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1 Structural basis for leucine-rich nuclear export signal recognition by CRM1 ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression Opposing action of casein kinase 1 and calcineurin in nucleo-cytoplasmic shuttling of mammalian translation initiation factor eIF6 A multifunctional domain in human CRM1 (exportin 1) mediates RanBP3 binding and multimerization of human T-cell leukemia virus type 1 Rex protein eEF1A is a novel component of the mammalian nuclear protein export machinery Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZ Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

P2860

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P2860

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

http://www.wikidata.org/entity/Q24685870

description

1999 nî lūn-bûn

@nan

1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Leptomycin B inactivates CRM1/ ...... n the central conserved region

@ast

Leptomycin B inactivates CRM1/ ...... n the central conserved region

@en

Leptomycin B inactivates CRM1/ ...... n the central conserved region

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type

label

Leptomycin B inactivates CRM1/ ...... n the central conserved region

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Leptomycin B inactivates CRM1/ ...... n the central conserved region

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Leptomycin B inactivates CRM1/ ...... n the central conserved region

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prefLabel

Leptomycin B inactivates CRM1/ ...... n the central conserved region

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Leptomycin B inactivates CRM1/ ...... n the central conserved region

@en

Leptomycin B inactivates CRM1/ ...... n the central conserved region

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PNAS.96.16.9112

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Proceedings of the National Academy of Sciences of the United States of America

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Leptomycin B inactivates CRM1/ ...... n the central conserved region

@en

P2093

B Wolff

http://www.w3.org/2001/XMLSchema#string

D Fujiwara

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E P Schreiner

http://www.w3.org/2001/XMLSchema#string

H Taoka

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S Horinouchi

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P2860

A novel class of RanGTP binding proteins

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins

Transformation of intact yeast cells treated with alkali cations

CRM1 is an export receptor for leucine-rich nuclear export signals

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

Exportin 1 (Crm1p) is an essential nuclear export factor.

Nucleocytoplasmic transport: the soluble phase

Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression

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9112-7

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scholarly article

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2381790

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10.1073/PNAS.96.16.9112

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16

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96

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Nobuaki Matsumori

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1999-08-03T00:00:00Z

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12868658

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10430904

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17741

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