p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways
about
Antiviral action of the tumor suppressor ARFTargeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target PtprvAnimal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for 100 YearsLoss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.Differential Plasma Glycoproteome of p19 Skin Cancer Mouse Model Using the Corra Label-Free LC-MS Proteomics PlatformTumors induce coordinate growth of artery, vein, and lymphatic vessel triads.p35 is required for CDK5 activation in cellular senescence.ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.Dynamics of ARF regulation that control senescence and cancer.Functional kinomics identifies candidate therapeutic targets in head and neck cancerInactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.Deregulation of FoxM1b leads to tumour metastasis.A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction.TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor developmentTumor suppressor genetics.Chronic centrosome amplification without tumorigenesis.p19Arf represses platelet-derived growth factor receptor β by transcriptional and posttranscriptional mechanisms.p53-Dependent and -independent functions of the Arf tumor suppressor.Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15A mouse model repository for cancer biomarker discoveryARF induces autophagy by virtue of interaction with Bcl-xl.Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activitiesProtective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53.Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.miR-34a is essential for p19(Arf)-driven cell cycle arrest.Transcriptional repression: the dark side of myc.p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.Arf tumor suppressor disrupts the oncogenic positive feedback loop including c-Myc and DDX5.The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis.An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosisAn inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.Chromosomal instability and phenotypic plasticity during the squamous-spindle carcinoma transition: association of a specific T(14;15) with malignant progression.P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway.
P2860
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P2860
p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
p19Arf suppresses growth, prog ...... dent and -independent pathways
@ast
p19Arf suppresses growth, prog ...... dent and -independent pathways
@en
p19Arf suppresses growth, prog ...... dent and -independent pathways
@nl
type
label
p19Arf suppresses growth, prog ...... dent and -independent pathways
@ast
p19Arf suppresses growth, prog ...... dent and -independent pathways
@en
p19Arf suppresses growth, prog ...... dent and -independent pathways
@nl
prefLabel
p19Arf suppresses growth, prog ...... dent and -independent pathways
@ast
p19Arf suppresses growth, prog ...... dent and -independent pathways
@en
p19Arf suppresses growth, prog ...... dent and -independent pathways
@nl
P2093
P2860
P1433
P1476
p19Arf suppresses growth, prog ...... dent and -independent pathways
@en
P2093
Christopher J Kemp
Karen S Kelly-Spratt
Kay E Gurley
Yutaka Yasui
P2860
P356
10.1371/JOURNAL.PBIO.0020242
P407
P577
2004-08-01T00:00:00Z