TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
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Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signalingBone specific immunity and its impact on metastasisTh-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis.TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer.Fucosylation is a promising target for cancer diagnosis and therapyEarly growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.Airway Inflammation after Bronchial Thermoplasty for Severe Asthma.TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitroGenetically engineered Newcastle disease virus expressing interleukin-2 and TNF-related apoptosis-inducing ligand for cancer therapy.Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impactCytosolic phospholipase A2 and lysophospholipids in tumor angiogenesisDeath receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 ExpressionMicrosatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.Loss of TRAIL-receptors is a recurrent feature in pancreatic cancer and determines the prognosis of patients with no nodal metastasis after surgery.Understanding the Role of the Death Receptor 5/FADD/caspase-8 Death Signaling in Cancer MetastasisTargeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis.A homeostatic switch in PACS-2 links membrane traffic to TRAIL-induced apoptosis.A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.Apoptosis, autophagy, necroptosis, and cancer metastasisRegulating TRAIL receptor-induced cell death at the membrane : a deadly discussionH3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.Control of FLIP(L) expression and TRAIL resistance by the extracellular signal-regulated kinase1/2 pathway in breast epithelial cells.Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them.Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapyDetachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis.Life and death by death receptors.Metastasis suppressor function of tumor necrosis factor-related apoptosis-inducing ligand-R in mice: implications for TRAIL-based therapy in humans?The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway.Following TRAIL's path in the immune system.Immune Regulation of the Metastatic Process: Implications for Therapy.TRAIL receptor signaling and therapeutics.Fucosylation and gastrointestinal cancer.Targeting the extrinsic apoptosis signaling pathway for cancer therapy.The therapeutic potential of TRAIL receptor signalling in cancer cells.TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.Sensitization of (colon) cancer cells to death receptor related therapies: a report from the FP6-ONCODEATH research consortium.
P2860
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P2860
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@ast
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@en
type
label
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@ast
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@en
prefLabel
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@ast
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@en
P2093
P2860
P356
P1476
TRAIL-R deficiency in mice enh ...... ting primary tumor development
@en
P2093
Andreea I Csernok
Anne Grosse-Wilde
Christopher J Kemp
Erich F Greiner
Gary M Longton
Günther Schütz
Henning Walczak
Oksana Voloshanenko
S Lawrence Bailey
Uta Schaefer
P2860
P304
P356
10.1172/JCI33061
P407
P577
2008-01-01T00:00:00Z