Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response
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Bacterial Toxins as Pathogen Weapons Against PhagocytesCellular and physiological effects of anthrax exotoxin and its relevance to disease.Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein.Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol.Sublethal doses of anthrax lethal toxin on the suppression of macrophage phagocytosis.Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxinAnthrax lethal toxin impairs CD1d-mediated antigen presentation by targeting the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway.IL-10 administration reduces PGE-2 levels and promotes CR3-mediated clearance of Escherichia coli K1 by phagocytes in meningitisProteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin.Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy.Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture.Suppression of dendritic cell activation by anthrax lethal toxin and edema toxin depends on multiple factors including cell source, stimulus used, and function testedErythrocytic mobilization enhanced by the granulocyte colony-stimulating factor is associated with reduced anthrax-lethal-toxin-induced mortality in mice.Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.Identification of toxin inhibitors using a magnetic nanosensor-based assay.Prophylaxis and therapy of inhalational anthrax by a novel monoclonal antibody to protective antigen that mimics vaccine-induced immunity.AB toxins: a paradigm switch from deadly to desirableEmergence of anthrax edema toxin as a master manipulator of macrophage and B cell functionsA Comparison of the Adaptive Immune Response between Recovered Anthrax Patients and Individuals Receiving Three Different Anthrax Vaccines.Haemophilus ducreyi partially activates human myeloid dendritic cellsAnthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms.Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.Contribution of toxins to the pathogenesis of inhalational anthrax.Bacillus anthracis: interactions with the host and establishment of inhalational anthrax.Discriminating virulence mechanisms among Bacillus anthracis strains by using a murine subcutaneous infection model.Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodiesEffect of Bacillus anthracis virulence factors on human dendritic cell activation.Anthrax edema toxin induces maturation of dendritic cells and enhances chemotaxis towards macrophage inflammatory protein 3beta.Prevention of immune cell apoptosis as potential therapeutic strategy for severe infections.Anthrax, toxins and vaccines: a 125-year journey targeting Bacillus anthracis.Cellular and systemic effects of anthrax lethal toxin and edema toxin.Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung modelsExpression of Nlrp1b inflammasome components in human fibroblasts confers susceptibility to anthrax lethal toxin.Defensive strategies of Bacillus anthracis that promote a fatal disease.The IL-23/Th17 axis is involved in the adaptive immune response to Bacillus anthracis in humans.Anthrax oedema toxin induces anthrax toxin receptor expression in monocyte-derived cells.Advances in structure determination by cryo-EM to unravel membrane-spanning pore formation
P2860
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P2860
Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@ast
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@en
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@nl
type
label
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@ast
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@en
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@nl
prefLabel
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@ast
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@en
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@nl
P2093
P2860
P3181
P1433
P1476
Anthrax lethal toxin-mediated ...... s the adaptive immune response
@en
P2093
Abdelkrim Alileche
Evan R Serfass
Jürgen Brojatsch
Stefan M Muehlbauer
P2860
P3181
P356
10.1371/JOURNAL.PPAT.0010019
P407
P577
2005-10-01T00:00:00Z