A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
about
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter releasePrimary afferent activation of thermosensitive TRPV1 triggers asynchronous glutamate release at central neuronsDynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon SynapsesSynaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesThe active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neuronsSynaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseNeurotransmitter release: the last millisecond in the life of a synaptic vesicleSyntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusionDistinct neuronal coding schemes in memory revealed by selective erasure of fast synchronous synaptic transmission.Calcium control of neurotransmitter releaseUnderstanding synapses: past, present, and futureCalmodulin suppresses synaptotagmin-2 transcription in cortical neuronsDoc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanismComplexin clamps asynchronous release by blocking a secondary Ca(2+) sensor via its accessory α helixCell biology of Ca2+-triggered exocytosisActivity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous releaseSV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosisSynaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreasGenetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosisComplexins: small but capableThe functional significance of synaptotagmin diversity in neuroendocrine secretionDistinct initial SNARE configurations underlying the diversity of exocytosisEnhancement of asynchronous release from fast-spiking interneuron in human and rat epileptic neocortexAstrocytes optimize the synaptic transmission of informationModelling vesicular release at hippocampal synapsesSynaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishmentAn organotypic slice culture to study the formation of calyx of Held synapses in-vitro.Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.Role of the synaptic ribbon in transmitting the cone light responseAsynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independent.Two modes of release shape the postsynaptic response at the inner hair cell ribbon synapsePresynaptic kainate receptor activation preserves asynchronous GABA release despite the reduction in synchronous release from hippocampal cholecystokinin interneuronsDevelopmental mechanisms for suppressing the effects of delayed release at the endbulb of Held.Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells.The type I inositol 1,4,5-trisphosphate receptor interacts with protein 4.1N to mediate neurite formation through intracellular Ca wavesIn vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter releaseStudying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system.
P2860
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P2860
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@ast
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@en
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@nl
type
label
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@ast
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@en
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@nl
prefLabel
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@ast
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@en
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
@en
P2093
Abigail T Fahim
Dengkui Qin
Jianyuan Sun
P2860
P2888
P304
P3181
P356
10.1038/NATURE06308
P407
P577
2007-11-29T00:00:00Z
P5875
P6179
1020700305