Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas
about
Glucagon secretion and signaling in the development of diabetesSynaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cellsSynaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon SynapsesSynaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesSynaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseNeurotransmitter release: the last millisecond in the life of a synaptic vesicleCalcium control of neurotransmitter releasePush-and-pull regulation of the fusion pore by synaptotagmin-7Cell biology of Ca2+-triggered exocytosisNeuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretionDifferential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter releaseActivity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10Pancreatic regulation of glucose homeostasisThe functional significance of synaptotagmin diversity in neuroendocrine secretionDistinct initial SNARE configurations underlying the diversity of exocytosisIncreased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretionSomatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channelsPalmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomesA manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology.Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.Lysosome-membrane fusion mediated superoxide production in hyperglycaemia-induced endothelial dysfunction.Model for glucagon secretion by pancreatic α-cells.Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23Altered islet morphology but normal islet secretory function in vitro in a mouse model with microvascular alterations in the pancreasExpression, localization, and functional role for synaptotagmins in pancreatic acinar cells.The genetic architecture of NAFLD among inbred strains of miceA computational systems analysis of factors regulating α cell glucagon secretion.Role of calcium and EPAC in norepinephrine-induced ghrelin secretion.Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells.ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.Segregation of neuronal and neuroendocrine differentiation in the sympathoadrenal lineage.RE-1 silencing transcription factor (REST): a regulator of neuronal development and neuronal/endocrine function.The molecular machinery of neurotransmitter release (Nobel lecture).Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation.Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7Effect of Cell Adhesion Molecule 1 Expression on Intracellular Granule Movement in Pancreatic α Cells.Glucagon-like peptide-1 drives energy metabolism on the synaptic highway.Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep Islets.C2-domain containing calcium sensors in neuroendocrine secretion.
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P2860
Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@ast
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@en
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@nl
type
label
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@ast
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@en
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@nl
prefLabel
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@ast
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@en
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@nl
P2093
P2860
P50
P1476
Synaptotagmin-7 is a principal ...... lucagon exocytosis in pancreas
@en
P2093
Dong Nhut Hoang
George K Radda
Quan Zhang
Shun-Hui Wei
Weiping Han
P2860
P304
P356
10.1113/JPHYSIOL.2008.168005
P407
P577
2009-03-15T00:00:00Z