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Toward more predictive genetic mouse models of Alzheimer's disease

Toward more predictive genetic mouse models of Alzheimer's disease

http://www.wikidata.org/entity/Q26771883

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Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments The Amyloid Cascade Hypothesis in Alzheimer's Disease: It's Time to Change Our Mind.Non human primate models for Alzheimer's disease-related research and drug discovery.Conserved regulators of cognitive aging: From worms to humans.Induced pluripotent stem cell technology: a decade of progress.Alzheimer's Disease: Biomarkers in the Genome, Blood, and Cerebrospinal Fluid.Comparative transcriptomics in human and mouse.Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead.APP mouse models for Alzheimer's disease preclinical studies.Assessment of Spontaneous Alternation, Novel Object Recognition and Limb Clasping in Transgenic Mouse Models of Amyloid-β and Tau Neuropathology CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.Studies for Improving a Rat Model of Alzheimer's Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory.Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation.Nonhuman Primate Models of Neurodegenerative Disorders.Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease.The role of neuroinflammation and amyloid in cognitive impairment in an APP/PS1 transgenic mouse model of Alzheimer's disease.Genome-editing applications of CRISPR-Cas9 to promote in vitro studies of Alzheimer's disease.Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies.Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer's Disease.Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer's Disease.APP21 transgenic rats develop age-dependent cognitive impairment and microglia accumulation within white matter tracts

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Toward more predictive genetic mouse models of Alzheimer's disease

http://www.wikidata.org/entity/Q26771883

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2016 nî lūn-bûn

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2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2016 թվականի ապրիլին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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Toward more predictive genetic mouse models of Alzheimer's disease

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J.BRAINRESBULL.2015.12.003

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Brain Research Bulletin

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Toward more predictive genetic mouse models of Alzheimer's disease

@en

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Gareth R Howell

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Michael Sasner

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Stacey J Sukoff Rizzo

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P2860

TREM2 Variants in Alzheimer's Disease

A call for transparent reporting to optimize the predictive value of preclinical research

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

Development, maintenance and disruption of the blood-brain barrier

The Glymphatic System: A Beginner's Guide

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

Neurodegenerative disease and adult neurogenesis

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease

CRISPR-Cas systems for editing, regulating and targeting genomes

Sleep drives metabolite clearance from the adult brain

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10.1016/J.BRAINRESBULL.2015.12.003

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2015-12-17T00:00:00Z

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Alzheimer's disease

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