Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
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Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's diseaseSerum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer diseaseMechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cellsSRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cellsThe homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequencesPericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain agingLow levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearanceToward more predictive genetic mouse models of Alzheimer's diseaseImpaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1The pericyte: a forgotten cell type with important implications for Alzheimer's disease?Notchless is required for axial skeleton formation in miceDisruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 alleleCerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's diseaseAn allelic series uncovers novel roles of the BRCT domain-containing protein PTIP in mouse embryonic vascular developmentReduction of circulating endothelial cells in peripheral blood of ALS patientsNeurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersCentral role for PICALM in amyloid-β blood-brain barrier transcytosis and clearanceProtective effects of low-intensity pulsed ultrasound on aluminum-induced cerebral damage in Alzheimer's disease rat model.Single-cell label-free photoacoustic flowoxigraphy in vivo.Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial DopplerChronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.The use of recently developed histochemical markers for localizing neurotoxicant induced regional brain pathologies.Central nervous system pericytes in health and disease.Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor.Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesisBrain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease.Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease.Anti-Tumoral Activity of a Short Decapeptide Fragment of the Alzheimer's Abeta Peptide.Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's diseaseVascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.Protection after stroke: cellular effectors of neurovascular unit integrity.MEOX2 regulates nuclear factor-kappaB activity in vascular endothelial cells through interactions with p65 and IkappaBbetaImpaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease.The science of stroke: mechanisms in search of treatments.Maximum principal strain and strain rate associated with concussion diagnosis correlates with changes in corpus callosum white matter indicesLow-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brainThe overlap between neurodegenerative and vascular factors in the pathogenesis of dementia
P2860
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P2860
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
name
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@ast
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@en
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@nl
type
label
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@ast
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@en
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@nl
prefLabel
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@ast
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@en
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@nl
P2093
P2860
P356
P1433
P1476
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
@en
P2093
Abhay Sagare
Andrew I. Brooks
Anna Rubio
Berislav V. Zlokovic
Florence Hofman
Jan Sallstrom
Nienwen Chow
P2860
P2888
P304
P356
10.1038/NM1287
P407
P577
2005-09-01T00:00:00Z