Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies - Test2 - elhamkhani - TriplyDB

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

http://www.wikidata.org/entity/Q26782052

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Expression and potential role of GATA factors in trophoblast development The emerging role of GATA transcription factors in development and disease Cancers Related to Immunodeficiencies: Update and Perspectives microRNA-200b as a Switch for Inducible Adult Angiogenesis Erythro-megakaryocytic transcription factors associated with hereditary anemia SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.GATA factor mutations in hematologic disease.GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene.The role of GATA2 in lethal prostate cancer aggressiveness.Absence of a simple code: how transcription factors read the genome Key regulators control distinct transcriptional programmes in blood progenitor and mast cells.MAGIA²: from miRNA and genes expression data integrative analysis to microRNA-transcription factor mixed regulatory circuits (2012 update).Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2 Conversion of human fibroblasts into monocyte-like progenitor cells.Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells Development and differentiation of the erythroid lineage in mammals GATA4 immunolocalization in breast carcinoma as a potent prognostic predictor.GATA2 deficiency.Spectrum of myeloid neoplasms and immune deficiency associated with germline GATA2 mutations.Epigenetic Determinants of Erythropoiesis: Role of the Histone Methyltransferase SetD8 in Promoting Erythroid Cell Maturation and Survival The Human Blood Metabolome-Transcriptome Interface GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders.GATA2 is required for lymphatic vessel valve development and maintenance.Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity GATA factors in endocrine neoplasia Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia Establishment of a cell-type-specific genetic network by the mediator complex component Med1.Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells Transcriptional mechanisms underlying hemoglobin synthesis.A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators.Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies.GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity.Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq.Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation.The biochemistry of hematopoietic stem cell development.

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Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

http://www.wikidata.org/entity/Q26782052

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2012 nî lūn-bûn

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Master regulatory GATA transcr ...... ks to hematologic malignancies

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Archibald S Perkins

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Emery H Bresnick

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Hsiang-Ying Lee

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Koichi R Katsumura

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Structure and ligand of a histone acetyltransferase bromodomain

A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction

A T-cell specific TCR delta DNA binding protein is a member of the human GATA family

Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

ETO2 coordinates cellular proliferation and differentiation during erythropoiesis

Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif

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