The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy
about
Autophagy in neurodegenerative diseases: from mechanism to therapeutic approachEssential role for autophagy in life span extensionPotential function for the Huntingtin protein as a scaffold for selective autophagy.Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.Energy restriction and potential energy restriction mimetics.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Engineered antibody therapies coming of age for aging brainsAutophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients.Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.Cardiac arrest triggers hippocampal neuronal death through autophagic and apoptotic pathways.ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.Induced Pluripotent Stem Cells in Huntington's Disease: Disease Modeling and the Potential for Cell-Based Therapy.Proteome-wide analysis of neural stem cell differentiation to facilitate transition to cell replacement therapies.Recent advances in autophagy-based neuroprotection.Primary cilia and autophagic dysfunction in Huntington's disease.iPSC-based drug screening for Huntington's disease.Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.Rab7 may be a novel therapeutic target for neurologic diseases as a key regulator in autophagy.Proteostasis of Huntingtin in Health and DiseaseRNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitationMethyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK.The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease.Functional amyloids: interrelationship with other amyloids and therapeutic assessment to treat neurodegenerative diseases.RNA-binding proteins in neurodegeneration: mechanisms in aggregate.Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson's Disease.Autophagy regulates exosomal release of prions in neuronal cells.
P2860
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P2860
The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The many faces of autophagy dy ...... ase: from mechanism to therapy
@ast
The many faces of autophagy dy ...... ase: from mechanism to therapy
@en
The many faces of autophagy dy ...... ase: from mechanism to therapy
@nl
type
label
The many faces of autophagy dy ...... ase: from mechanism to therapy
@ast
The many faces of autophagy dy ...... ase: from mechanism to therapy
@en
The many faces of autophagy dy ...... ase: from mechanism to therapy
@nl
prefLabel
The many faces of autophagy dy ...... ase: from mechanism to therapy
@ast
The many faces of autophagy dy ...... ase: from mechanism to therapy
@en
The many faces of autophagy dy ...... ase: from mechanism to therapy
@nl
P2860
P3181
P1433
P1476
The many faces of autophagy dy ...... ase: from mechanism to therapy
@en
P2093
Albert R. La Spada
Constanza J. Cortes
P2860
P304
P3181
P356
10.1016/J.DRUDIS.2014.02.014
P407
P577
2014-07-01T00:00:00Z