The public road to high-quality curated biological pathwaysTargeting TNF: a therapeutic strategy for Alzheimer's diseaseImpact of recent innovations in the use of mass cytometry in support of drug developmentTargeting the mTOR kinase domain: the second generation of mTOR inhibitorsOrphan nuclear receptors in drug discoveryExpanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)Structural features of subtype-selective EP receptor modulatorsAlternative RNA splicing: contribution to pain and potential therapeutic strategyTransparency in drug regulation: public assessment reports in Europe and AustraliaOpen for collaboration: an academic platform for drug discovery and development at SciLifeLabPathophysiological implications of neurovascular P450 in brain disordersExcessive intimal hyperplasia in human coronary arteries before intimal lipid depositions is the initiation of coronary atherosclerosis and constitutes a therapeutic targetProtein crystallization screens developed at the MRC Laboratory of Molecular BiologyRecent developments in using mechanistic cardiac modelling for drug safety evaluationThe glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of actionTranslational Medicine Guide transforms drug development processes: the recent Merck experienceChallenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugsChallenges and opportunities for non-antibody scaffold drugsModelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectivesAllergy immunotherapy: the future of allergy treatmentReactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancerCan residence time offer a useful strategy to target agonist drugs for sustained GPCR responses?Regeneration of stalled immune responses to transformed and infected cells using γδ T cellsThe many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapyTargeting IL-34 in chronic inflammationA conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomicsStructure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problemDiscoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discoveryEmergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterialsRecent progress in structure-based anti-influenza drug designRestoration of mitochondria function as a target for cancer therapyFactor XI as a target for antithrombotic therapyDREADDs: novel tools for drug discovery and developmentFunction and regulation of large conductance Ca(2+)-activated K+ channel in vascular smooth muscle cellsThe Tox21 robotic platform for the assessment of environmental chemicals--from vision to realityReversal of target-specific oral anticoagulantsTargeting the Wnt signaling pathways in pulmonary arterial hypertensionFinding a better path to drug selectivityConnections in pharmacology: innovation serving translational medicineTowards the use of hydrogels in the treatment of limbal stem cell deficiency
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P1433
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begutachtete wissenschaftliche Zeitschrift
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peer-reviewed scientific journal
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revista científica
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rivista scientifica
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vědecký časopis
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wetenschappelijk tijdschrift van Elsevier
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рецензований науковий журнал
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वैज्ञानिक पत्रिका
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discov. Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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Drug Discovery Today
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P3181
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Drug Discovery Today
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1996-01-01T00:00:00Z
P5963
drug-discovery-today